• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

急性埃博拉病毒感染消退两年多后精液中埃博拉病毒核糖核酸的检测

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection.

作者信息

Fischer William A, Brown Jerry, Wohl David Alain, Loftis Amy James, Tozay Sam, Reeves Edwina, Pewu Korto, Gorvego Galapaki, Quellie Saturday, Cunningham Coleen K, Merenbloom Carson, Napravnik Sonia, Dube Karine, Adjasoo David, Jones Erin, Bonarwolo Korlia, Hoover David

机构信息

Divisions of Pulmonary and Critical Care Medicine and.

Eternal Love Winning Africa Hospital, Monrovia, Liberia.

出版信息

Open Forum Infect Dis. 2017 Jul 22;4(3):ofx155. doi: 10.1093/ofid/ofx155. eCollection 2017 Summer.

DOI:10.1093/ofid/ofx155
PMID:29670927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5897835/
Abstract

Among 149 men who survived Ebola virus disease (EVD) and donated semen 260-1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.

摘要

在149名埃博拉病毒病（EVD）幸存者中，他们在EVD发病后260 - 1016天捐献了精液，其中13人（9%）检测到埃博拉病毒（EBOV）核糖核酸（RNA）。在137名EVD发病2年后捐献精液的男性中，11人（8%）的精液标本EBOV RNA呈阳性。EBOV RNA在精液中持续存在的潜在机制尚不清楚，而且病毒RNA的检测是否代表有传染性病毒也不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cad/5897835/e2ec16598893/ofx15501.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cad/5897835/e2ec16598893/ofx15501.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cad/5897835/e2ec16598893/ofx15501.jpg

相似文献

1
Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection.急性埃博拉病毒感染消退两年多后精液中埃博拉病毒核糖核酸的检测
Open Forum Infect Dis. 2017 Jul 22;4(3):ofx155. doi: 10.1093/ofid/ofx155. eCollection 2017 Summer.
2
Ebola Virus Persistence in Semen of Male Survivors.埃博拉病毒在男性幸存者精液中的持续存在。
Clin Infect Dis. 2016 Jun 15;62(12):1552-1555. doi: 10.1093/cid/ciw202. Epub 2016 Apr 3.
3
The impact of semen testing for Ebola virus RNA on sexual behavior of male Ebola survivors in Liberia.利比里亚埃博拉幸存者精液检测埃博拉病毒 RNA 对其性行为的影响。
PLoS Negl Trop Dis. 2020 Sep 14;14(9):e0008556. doi: 10.1371/journal.pntd.0008556. eCollection 2020 Sep.
4
A 40-Month Follow-Up of Ebola Virus Disease Survivors in Guinea (PostEbogui) Reveals Long-Term Detection of Ebola Viral Ribonucleic Acid in Semen and Breast Milk.几内亚埃博拉病毒病幸存者40个月随访（PostEbogui）显示，精液和母乳中长期检测到埃博拉病毒核糖核酸。
Open Forum Infect Dis. 2019 Nov 8;6(12):ofz482. doi: 10.1093/ofid/ofz482. eCollection 2019 Dec.
5
High doses of favipiravir in two men survivors of Ebola virus disease carrying Ebola virus in semen in Guinea.几内亚两名埃博拉病毒病男性幸存者精液中携带埃博拉病毒，接受高剂量法匹拉韦治疗。
IDCases. 2022 Jan 21;27:e01412. doi: 10.1016/j.idcr.2022.e01412. eCollection 2022.
6
Ebola Virus RNA in Semen from an HIV-Positive Survivor of Ebola.一名埃博拉病毒阳性幸存者精液中的埃博拉病毒RNA
Emerg Infect Dis. 2017 Apr;23(4):714-715. doi: 10.3201/eid2304.161743. Epub 2017 Apr 15.
7
New Evidence of Long-lasting Persistence of Ebola Virus Genetic Material in Semen of Survivors.新证据表明埃博拉病毒遗传物质在幸存者精液中存在持久。
J Infect Dis. 2016 Nov 15;214(10):1475-1476. doi: 10.1093/infdis/jiw078. Epub 2016 May 3.
8
Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut.对血液和口腔拭子样本中的RNA进行深度测序，揭示了急性埃博拉病毒病患者体内存在多种病原体的核酸，且与细菌通过肠道的易位现象相符。
mSphere. 2017 Aug 23;2(4). doi: 10.1128/mSphereDirect.00325-17. eCollection 2017 Jul-Aug.
9
Serological Investigation of Laboratory-Confirmed and Suspected Ebola Virus Disease Patients During the Late Phase of the Ebola Outbreak in Sierra Leone.塞拉利昂埃博拉疫情后期实验室确诊和疑似埃博拉病毒病患者的血清学调查。
Virol Sin. 2018 Aug;33(4):323-334. doi: 10.1007/s12250-018-0044-z. Epub 2018 Jul 31.
10
Anti-Ebola Virus Antibody Levels in Convalescent Plasma and Viral Load After Plasma Infusion in Patients With Ebola Virus Disease.埃博拉病毒病患者输注恢复期血浆后病毒载量和抗埃博拉病毒抗体水平的变化。
J Infect Dis. 2018 Jul 13;218(4):555-562. doi: 10.1093/infdis/jiy199.

引用本文的文献

1
Environmental stress drives clearance of a persistent enteric virus in mice.环境应激促使小鼠体内持续性肠道病毒的清除。
Nat Microbiol. 2025 Jun 25. doi: 10.1038/s41564-025-02046-z.
2
Efficacy of Polyphenylene Carboxymethylene (PPCM) Gel at Protecting Type I Interferon Receptors Knockout Mice from Intravaginal Ebola Virus Challenge.聚亚苯基羧甲基乙烯（PPCM）凝胶对I型干扰素受体敲除小鼠在阴道内感染埃博拉病毒时的保护效果。
Viruses. 2024 Oct 30;16(11):1693. doi: 10.3390/v16111693.
3
Can Marburg virus be sexually transmitted?马尔堡病毒会通过性传播吗？

本文引用的文献

1
Ebola Virus RNA in Semen from an HIV-Positive Survivor of Ebola.一名埃博拉病毒阳性幸存者精液中的埃博拉病毒RNA
Emerg Infect Dis. 2017 Apr;23(4):714-715. doi: 10.3201/eid2304.161743. Epub 2017 Apr 15.
2
Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study.埃博拉病毒病幸存者精液中埃博拉病毒 RNA 的持续存在和清除：纵向分析和建模研究。
Lancet Glob Health. 2017 Jan;5(1):e80-e88. doi: 10.1016/S2214-109X(16)30243-1.
3
Validation of the Cepheid GeneXpert for Detecting Ebola Virus in Semen.
Health Sci Rep. 2024 Aug 2;7(8):e2270. doi: 10.1002/hsr2.2270. eCollection 2024 Aug.
4
ZMapp reduces diffusion of Ebola viral particles in fresh human cervicovaginal mucus.ZMapp 减少了新鲜人宫颈阴道黏液中埃博拉病毒颗粒的扩散。
Emerg Microbes Infect. 2024 Dec;13(1):2352520. doi: 10.1080/22221751.2024.2352520. Epub 2024 May 16.
5
The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection.BALB/c 小鼠对适应鼠类的埃博拉病毒阴道感染的易感性。
Viruses. 2023 Jul 21;15(7):1590. doi: 10.3390/v15071590.
6
Atypical Ebola Virus Disease in a Rhesus Macaque.在恒河猴中出现的非典型埃博拉病毒病。
J Infect Dis. 2023 Nov 13;228(Suppl 7):S617-S625. doi: 10.1093/infdis/jiad283.
7
A Single Case Observation: Is the Ebola Virus Soluble Glycoprotein an Indicator of Viral Recrudescence?一项单病例观察：埃博拉病毒可溶性糖蛋白是否为病毒复发的指标？
J Infect Dis. 2023 Nov 13;228(Suppl 7):S631-S634. doi: 10.1093/infdis/jiad279.
8
The role of immune activation and antigen persistence in acute and long COVID.免疫激活和抗原持续存在在急性和长新冠中的作用。
J Investig Med. 2023 Jun;71(5):545-562. doi: 10.1177/10815589231158041. Epub 2023 Mar 6.
9
Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals.研究埃博拉病毒感染和抗病毒药物测试的人原代阴道上皮细胞气液界面模型的建立。
Antiviral Res. 2023 Mar;211:105551. doi: 10.1016/j.antiviral.2023.105551. Epub 2023 Jan 31.
10
Viral Infections and Male Infertility: A Comprehensive Review of the Role of Oxidative Stress.病毒感染与男性不育：氧化应激作用的综合综述
Front Reprod Health. 2022 Feb 3;4:782915. doi: 10.3389/frph.2022.782915. eCollection 2022.
赛沛GeneXpert检测精液中埃博拉病毒的验证
J Infect Dis. 2017 Feb 1;215(3):344-350. doi: 10.1093/infdis/jiw562.
4
Extraordinary long-term and fluctuating persistence of Ebola virus RNA in semen of survivors in Guinea: implications for public health.几内亚埃博拉病毒幸存者精液中埃博拉病毒RNA的超长且波动的持续存在：对公共卫生的影响
Clin Microbiol Infect. 2017 Jun;23(6):412-413. doi: 10.1016/j.cmi.2016.11.005. Epub 2016 Nov 17.
5
Prevention of sexual transmission of Ebola in Liberia through a national semen testing and counselling programme for survivors: an analysis of Ebola virus RNA results and behavioural data.通过为幸存者提供国家精液检测和咨询方案预防利比里亚埃博拉病毒的性传播：埃博拉病毒 RNA 结果和行为数据的分析。
Lancet Glob Health. 2016 Oct;4(10):e736-43. doi: 10.1016/S2214-109X(16)30175-9. Epub 2016 Aug 30.
6
Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days.几内亚埃博拉病毒病的卷土重来与一名精液中病毒持续存在超过500天的幸存者有关。
Clin Infect Dis. 2016 Nov 15;63(10):1353-1356. doi: 10.1093/cid/ciw601. Epub 2016 Sep 1.
7
Late Ebola virus relapse causing meningoencephalitis: a case report.晚期埃博拉病毒复发致脑膜脑炎：一例报告
Lancet. 2016 Jul 30;388(10043):498-503. doi: 10.1016/S0140-6736(16)30386-5. Epub 2016 May 18.
8
New Evidence of Long-lasting Persistence of Ebola Virus Genetic Material in Semen of Survivors.新证据表明埃博拉病毒遗传物质在幸存者精液中存在持久。
J Infect Dis. 2016 Nov 15;214(10):1475-1476. doi: 10.1093/infdis/jiw078. Epub 2016 May 3.
9
Confronting Ebola as a Sexually Transmitted Infection.将埃博拉视为性传播感染来应对。
Clin Infect Dis. 2016 May 15;62(10):1272-6. doi: 10.1093/cid/ciw123. Epub 2016 Mar 1.
10
Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors - Final Report.埃博拉病毒病幸存者精液中埃博拉病毒RNA的持续存在——最终报告
N Engl J Med. 2017 Oct 12;377(15):1428-1437. doi: 10.1056/NEJMoa1511410. Epub 2015 Oct 14.