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急性埃博拉病毒感染消退两年多后精液中埃博拉病毒核糖核酸的检测

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection.

作者信息

Fischer William A, Brown Jerry, Wohl David Alain, Loftis Amy James, Tozay Sam, Reeves Edwina, Pewu Korto, Gorvego Galapaki, Quellie Saturday, Cunningham Coleen K, Merenbloom Carson, Napravnik Sonia, Dube Karine, Adjasoo David, Jones Erin, Bonarwolo Korlia, Hoover David

机构信息

Divisions of Pulmonary and Critical Care Medicine and.

Eternal Love Winning Africa Hospital, Monrovia, Liberia.

出版信息

Open Forum Infect Dis. 2017 Jul 22;4(3):ofx155. doi: 10.1093/ofid/ofx155. eCollection 2017 Summer.

Abstract

Among 149 men who survived Ebola virus disease (EVD) and donated semen 260-1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.

摘要

在149名埃博拉病毒病(EVD)幸存者中,他们在EVD发病后260 - 1016天捐献了精液,其中13人(9%)检测到埃博拉病毒(EBOV)核糖核酸(RNA)。在137名EVD发病2年后捐献精液的男性中,11人(8%)的精液标本EBOV RNA呈阳性。EBOV RNA在精液中持续存在的潜在机制尚不清楚,而且病毒RNA的检测是否代表有传染性病毒也不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cad/5897835/e2ec16598893/ofx15501.jpg

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