不同经皮植入物对脱矿骨基质诱导活性的抑制作用。
Inhibition of the inductive activity of demineralized bone matrix by different percutaneous implants.
作者信息
Uretzky G, Appelbaum J, Sela J
机构信息
Joseph Lunenfeld Cardiac Surgery Research Center, Hadassah University Hospital, Jerusalem, Israel.
出版信息
Biomaterials. 1988 Mar;9(2):195-7. doi: 10.1016/0142-9612(88)90122-6.
Teflon tubes with either Gore-Tex (PTFE) or Dacron felt sleeves were implanted percutaneously in rats, in conjunction with demineralized bone matrix. This resulted in different inflammatory reactions, as well as in chondrogenesis and osteogenesis in the subcutaneous tissues. Although induction of osteogenesis by the demineralized bone matrix in the vicinity of the foreign material was inhibited, circumferential bone formation was highly reproducible. The prospect of utilizing demineralized bone matrix in order to enhance acceptance of percutaneous tubes is discussed.
将带有 Gore-Tex（聚四氟乙烯）或涤纶毡套的聚四氟乙烯管经皮植入大鼠体内，并结合脱矿骨基质。这导致了不同的炎症反应，以及皮下组织中的软骨生成和骨生成。尽管异物附近的脱矿骨基质诱导骨生成受到抑制，但环形骨形成具有高度可重复性。本文讨论了利用脱矿骨基质来提高经皮管耐受性的前景。
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