Gatling W, Mullee M A, Hill R D
Poole General Hospital, UK.
Diabet Med. 1988 Apr;5(3):256-60. doi: 10.1111/j.1464-5491.1988.tb00980.x.
All the known diabetic patients (917) from a defined population (90,660) were called for review by a single observer. A total of 842 (92%) attended and proteinuria, identified using Albustix (0.3 g/l or more), was found in 57 cases (6.8%), but in 9 this was in association with a urinary tract infection. Diastolic blood pressure, an ulcerated or amputated lower limb, and smoking category were found to be the only significant predictors of proteinuria after a multiple logistic regression analysis. A serum creatinine greater than 150 mumol/l was found in 29 (3.8%) of the 768 diabetics in whom it was measured. However, proteinuria was only present in 7 of the diabetics with impaired renal function. In those aged less than 65 years, the prevalence of proteinuria with impaired renal function was 0.75%.
来自特定人群(90,660人)的所有已知糖尿病患者(917人)由一名观察者召集进行复查。共有842人(92%)前来就诊,使用尿蛋白试纸(0.3 g/l及以上)检测发现57例(6.8%)存在蛋白尿,但其中9例与尿路感染有关。经过多元逻辑回归分析,发现舒张压、下肢溃疡或截肢以及吸烟类别是蛋白尿的唯一显著预测因素。在768名接受检测的糖尿病患者中,有29人(3.8%)血清肌酐大于150 μmol/l。然而,肾功能受损的糖尿病患者中只有7人存在蛋白尿。在年龄小于65岁的人群中,肾功能受损伴蛋白尿的患病率为0.75%。