Hombach V, Höher M, Höpp H W, Kochs M, Eggeling T, Osypka P, Hilger H H
Abteilung Innere Medizin IV (Kardiologie-Angiologie-Pneumologie), Universität Ulm.
Dtsch Med Wochenschr. 1988 May 20;113(20):801-5. doi: 10.1055/s-2008-1067725.
After extensive animal experiments a new method of high-frequency current coronary angioplasty (HFCA) via a specially developed catheter system was used in ten patients with haemodynamically significant coronary artery stenoses. In eight patients the stenoses affected the anterior interventricular branch (AIVB), in one patient each the circumflex branch and the right coronary artery, respectively. In nine patients the stenosis cross-section was reduced by at least 20% (from a mean of 91.9% +/- 5.8% to 52.6 +/- 17.5%). In three patients HFCA was followed by balloon angioplasty. The total number of applications per patient ranged from 3 to 12 (mean total duration of current flow: 3.9 +/- 1.0 s). There was only one severe complication, in a patient with subtotal AIVB occlusion after initially successful HFCA: balloon angioplasty successfully restored the lumen to the post-HFCA state. The new technique of HFCA is worthy of further development. It promises to be a valuable addition or alternative to balloon coronary angioplasty.
在进行了广泛的动物实验后，一种通过专门研发的导管系统进行高频电流冠状动脉血管成形术（HFCA）的新方法被应用于10例有血流动力学意义的冠状动脉狭窄患者。8例患者的狭窄发生在前室间支（AIVB），各有1例患者的狭窄分别发生在旋支和右冠状动脉。9例患者的狭窄横截面积减少了至少20%（从平均91.9%±5.8%降至52.6±17.5%）。3例患者在HFCA后进行了球囊血管成形术。每位患者的应用总次数为3至12次（平均总电流持续时间：3.9±1.0秒）。仅出现1例严重并发症，在1例最初HFCA成功但AIVB次全闭塞的患者中：球囊血管成形术成功将管腔恢复至HFCA后的状态。HFCA新技术值得进一步研发。它有望成为球囊冠状动脉血管成形术的一种有价值的补充或替代方法。
