Distler W, Schwenzer T, Umbach G, Graf M
Universitäts-Frauenklinik Düsseldorf.
Geburtshilfe Frauenheilkd. 1988 Mar;48(3):140-2. doi: 10.1055/s-2008-1035712.
Umbilical venous plasma concentrations of beta-endorphin in 20 premature and 30 mature newborn infants after vaginal delivery or elective caesarean section were determined by specific RIA. In the premature infants the beta-endorphin levels after vaginal and abdominal delivery were significantly higher than in mature newborns. Our data indicate that for premature infants the delivery is more stressful and therefore most likely the release of beta-endorphin from the pituitary is more pronounced. Since high opioid levels can cause respiratory and circulatory difficulties, premature infants are exposed to risk of these problems.
采用特异性放射免疫分析法测定了20例早产儿和30例足月儿经阴道分娩或择期剖宫产术后脐静脉血浆β-内啡肽浓度。早产儿经阴道分娩和剖宫产术后的β-内啡肽水平显著高于足月儿。我们的数据表明，对于早产儿来说，分娩压力更大，因此垂体释放β-内啡肽的情况很可能更明显。由于高阿片类物质水平会导致呼吸和循环困难，早产儿面临这些问题的风险。
