Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, 44, Wenhuaxi Street, Jinan 250012, China.
Health and Family Planning Information Center of Shandong Province, 75, Yuhan Street, Jinan 250002, China.
Int J Environ Res Public Health. 2018 Apr 17;15(4):774. doi: 10.3390/ijerph15040774.
Although there is growing evidence linking chronic obstructive pulmonary disease (COPD) hospital admissions to the exposure to ambient air pollution, the effect can vary depending on the local geography, pollution type, and pollution level. The number of large-scale multicity studies remains limited in China. This study aims to assess the short-term effects of ambient air pollution (PM, PM, SO₂, NO₂) on chronic obstructive pulmonary disease hospital admissions from 2015 to 2016, with a total of 216,159 records collected from 207 hospitals in 17 cities all over the Shandong province, east China. Generalized additive models and penalized splines were applied to study the data whilst controlling for confounding meteorological factors and long-term trends. The air pollution was analyzed with 0–6 day lag effects and the percentage change of hospital admissions was assessed for a 10-μg/m³ increase in the air pollution levels. We also examined the percentage changes for different age groups and gender, respectively. The results showed that air pollution was significantly associated with adverse health outcomes and stronger effects were observed for females. The air pollution health effects were also impacted by geographical factors such that the air pollution had weaker health effects in coastal cities.
尽管越来越多的证据表明慢性阻塞性肺疾病（COPD）住院与暴露于环境空气污染有关，但这种影响可能因当地地理、污染类型和污染水平而异。中国开展的大规模多城市研究数量仍然有限。本研究旨在评估 2015 年至 2016 年环境空气污染（PM、PM、SO₂、NO₂）对山东省 17 个城市 207 家医院共 216159 例 COPD 住院的短期影响。应用广义加性模型和惩罚样条来研究数据，同时控制混杂的气象因素和长期趋势。对空气污染进行了 0-6 天的滞后效应分析，并评估了空气污染水平每增加 10-μg/m³时住院人数的百分比变化。我们还分别检查了不同年龄组和性别的百分比变化。结果表明，空气污染与不良健康结果显著相关，女性的影响更强。空气污染的健康影响也受到地理因素的影响，例如在沿海城市，空气污染的健康影响较弱。
