Biozentrum, University of Basel, Basel CH-4056, Switzerland.
Biozentrum, University of Basel, Basel CH-4056, Switzerland.
Neuron. 2018 Apr 18;98(2):246-248. doi: 10.1016/j.neuron.2018.04.005.
Obernier et al. (2018) show that the primary mode of division of adult ventricular-subventricular zone (V-SVZ) neural stem cells is symmetric, with the majority generating two non-stem cell progeny, and a minority self-renewing. This discovery has important implications for understanding stem cell dynamics and adult neurogenesis.
奥伯尼尔等人(2018 年)表明,成年脑室下区(V-SVZ)神经干细胞的主要分裂方式为对称分裂,多数细胞产生两个非干细胞后代,少数细胞自我更新。这一发现对理解干细胞动力学和成年神经发生具有重要意义。