Hanumunthadu Daren, Ruiz-Medrano Jorge, Dumpala Sunila, Jabeen Ayesha, Jabeen Asiya, Goud Abhilash, Ruiz-Moreno José M, Chhablani Jay
Moorfields Eye Hospital National Health Service Foundation Trust, London, EC1V 2PD, United Kingdom.
Ophthalmology Unit, Clínico San Carlos University Hospital, Madrid 28040, Spain.
Int J Ophthalmol. 2018 Apr 18;11(4):681-686. doi: 10.18240/ijo.2018.04.24. eCollection 2018.
To evaluate choroidal thickness, medium choroidal vessel thickness (MCVT) and large choroidal vessel thickness (LCVT) in normal children and adult subjects.
Manual measurements of subfoveal choroidal thickness (SFCT), MCVT and LCVT at subfoveal and 750 µm nasal and temporal to fovea locations were completed on enhanced-depth imaging optical coherence tomography (EDI-OCT) scans of normal children and adult subjects.
Fifty adult and fifty-seven child subjects were included in the study (including 80 adult and 103 child eyes). Mean (±SD) SFCT of adult and children eyes in the study was 309.3±95.7 µm and 279.3±50.4 µm respectively. SFCT and subfoveal MCVT in adult eyes were significantly more than children (=0.01 and ≤0.0001 respectively).
There is choroidal thickening with associated thickening of medium choroidal vessels in adults, suggesting that there is alteration in choroidal vasculature with ageing.
评估正常儿童和成人受试者的脉络膜厚度、脉络膜中层血管厚度（MCVT）和脉络膜大血管厚度（LCVT）。
在正常儿童和成人受试者的增强深度成像光学相干断层扫描（EDI-OCT）上，对黄斑中心凹下脉络膜厚度（SFCT）、MCVT和LCVT进行手动测量，测量位置包括黄斑中心凹下以及黄斑中心凹鼻侧和颞侧750 µm处。
本研究纳入了50名成人和57名儿童受试者（包括80只成人眼和103只儿童眼）。研究中成人眼和儿童眼的平均（±标准差）SFCT分别为309.3±95.7 µm和279.3±50.4 µm。成人眼中的SFCT和黄斑中心凹下MCVT显著高于儿童（分别为P = 0.01和P≤0.0001）。
成人存在脉络膜增厚以及脉络膜中层血管增厚，提示脉络膜血管系统随年龄增长发生了改变。
