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[正电子发射断层扫描原理]

[Principles of PET].

作者信息

Beuthien-Baumann B

机构信息

Abteilung Radiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland.

出版信息

Radiologe. 2018 May;58(5):487-500. doi: 10.1007/s00117-018-0380-x.

DOI:10.1007/s00117-018-0380-x
PMID:29675694
Abstract

Positron emission tomography (PET) is a procedure in nuclear medicine, which is applied predominantly in oncological diagnostics. In the form of modern hybrid machines, such as PET computed tomography (PET/CT) and PET magnetic resonance imaging (PET/MRI) it has found wide acceptance and availability. The PET procedure is more than just another imaging technique, but a functional method with the capability for quantification in addition to the distribution pattern of the radiopharmaceutical, the results of which are used for therapeutic decisions. A profound knowledge of the principles of PET including the correct indications, patient preparation, and possible artifacts is mandatory for the correct interpretation of PET results.

摘要

正电子发射断层扫描(PET)是核医学中的一种检查方法,主要应用于肿瘤诊断。以现代混合型设备的形式,如PET计算机断层扫描(PET/CT)和PET磁共振成像(PET/MRI),它已得到广泛认可并得以普及。PET检查不仅仅是另一种成像技术,而是一种功能方法,除了放射性药物的分布模式外还具备定量能力,其结果用于治疗决策。要正确解读PET结果,必须深入了解PET的原理,包括正确的适应症、患者准备以及可能出现的伪影。

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J Nucl Med. 2017 Nov;58(11):1770-1775. doi: 10.2967/jnumed.117.190736. Epub 2017 May 4.
2
Brain Tumors: An Update on Clinical PET Research in Gliomas.脑肿瘤:胶质瘤临床正电子发射断层显像(PET)研究的最新进展
Semin Nucl Med. 2017 Jan;47(1):5-17. doi: 10.1053/j.semnuclmed.2016.09.004. Epub 2016 Sep 27.
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The Rise of PSMA Ligands for Diagnosis and Therapy of Prostate Cancer.用于前列腺癌诊断和治疗的PSMA配体的兴起
J Nucl Med. 2016 Oct;57(Suppl 3):79S-89S. doi: 10.2967/jnumed.115.170720.
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Q J Nucl Med Mol Imaging. 2016 Sep;60(3):219-35. Epub 2016 Jun 9.
6
Patient preparation for cardiac fluorine-18 fluorodeoxyglucose positron emission tomography imaging of inflammation.用于炎症的心脏氟-18氟脱氧葡萄糖正电子发射断层显像的患者准备
J Nucl Cardiol. 2017 Feb;24(1):86-99. doi: 10.1007/s12350-016-0502-7. Epub 2016 Jun 8.
7
An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET.肿瘤学FDG PET中肿瘤与肝脏比值(TLR)和肿瘤与血液标准化摄取值比值(SUR)之间关系的研究。
EJNMMI Res. 2016 Dec;6(1):19. doi: 10.1186/s13550-016-0174-y. Epub 2016 Mar 2.
8
Response to Early Treatment Evaluated with 18F-FDG PET and PERCIST 1.0 Predicts Survival in Patients with Ewing Sarcoma Family of Tumors Treated with a Monoclonal Antibody to the Insulinlike Growth Factor 1 Receptor.采用18F-FDG PET和PERCIST 1.0评估早期治疗反应可预测接受胰岛素样生长因子1受体单克隆抗体治疗的尤因肉瘤家族性肿瘤患者的生存情况。
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