Hess Markus M, Fleischer Susanne, Ernstberger Marcel
Deutsche Stimmklinik (German Voice Clinic), Martinistrasse 64, 20251, Hamburg, Germany.
Department of Voice, Speech and Hearing Disorders, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Eur Arch Otorhinolaryngol. 2018 Jun;275(6):1557-1567. doi: 10.1007/s00405-018-4974-8. Epub 2018 Apr 19.
Photoangiolytic lasers have broadened the surgical armamentarium for many phonosurgical interventions. However, the pulse dye laser and potassium titanyl phosphate (KTP) laser have technical drawbacks and a smaller spectrum of indications.
The new 445 nm wavelength laser, the so-called 'blue laser', proves to show tissue effects comparable to the KTP laser and is also capable of treating subepithelial vessels due to its photoangiolytic properties, it can coagulate and carbonize at higher energy levels, and can be used via glass fibers in non-contact and contact mode for in-office procedures.
In contrast to the KTP, the new 445 nm laser can also be used as a cutting laser, thus combining very much wanted properties of diode or CO2 lasers with photoangiolytic lasers. Further advantages of the new laser are the; (1) portability of the shoe box sized, shock-proof laser machine for in-office and operating room usage, (2) the selection of pulse rates from continuous wave (cw) to less than a millisecond, (3) stronger tissue effects compared to KTP with similar energy and pulse settings, (4) far better cutting properties than the KTP, and thus (5) more possibilities for usage in laryngology as well as in other fields or surgery.
We demonstrate the feasibility of the 445 nm laser in several laboratory experiments and show clinical cases where photoangiolysis and cutting was possible. However, this is a preliminary report and further systematic studies in greater numbers are warranted.
光血管溶解激光拓宽了许多嗓音外科手术的器械库。然而,脉冲染料激光和磷酸钛氧钾(KTP)激光存在技术缺陷且适应证范围较窄。
新型445纳米波长激光,即所谓的“蓝光激光”,被证明具有与KTP激光相当的组织效应,并且由于其光血管溶解特性,还能够治疗上皮下血管,它在较高能量水平下可凝固和碳化,并且可通过玻璃纤维以非接触和接触模式用于门诊手术。
与KTP激光不同,新型445纳米激光还可作为切割激光使用,从而将二极管或二氧化碳激光非常理想的特性与光血管溶解激光相结合。这种新型激光的其他优点包括:(1)鞋盒大小、防震的激光设备便于携带,可用于门诊和手术室;(2)脉冲频率可从连续波(cw)选择到小于一毫秒;(3)在相似能量和脉冲设置下,与KTP激光相比组织效应更强;(4)切割性能远优于KTP激光,因此(5)在喉科学以及其他外科领域有更多应用可能性。
我们在多个实验室实验中证明了445纳米激光的可行性,并展示了能够进行光血管溶解和切割的临床病例。然而,这是一份初步报告,需要进行更多进一步的系统研究。