Orakwe Dubem Ejikeme, Tijani Kehinde Habeeb, Jeje Emmauel Ajibola, Ogunjimi Moses Adebisi, Rufus Wale Ojewola, Alabi Taiwo Opeyemi
Department of Surgery, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra, Nigeria.
Department of Surgery, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria.
Niger Postgrad Med J. 2018 Jan-Mar;25(1):43-47. doi: 10.4103/npmj.npmj_169_17.
Bilateral subcapsular orchiectomy (BSO) is said to be more aesthetic and psychologically satisfying when compared to bilateral total orchiectomy (BTO). This study compared the quality of life (QoL) of men with advanced prostate cancer who had BTO to those who had BSO, with an emphasis on their perception of self or identity as a man.
Sixty-one patients with advanced prostate cancer opting for bilateral orchiectomy were recruited. Pre-orchiectomy and at 1 month and 3 months post-orchiectomy, the Functional Assessment of Cancer Therapy for Prostate cancer (FACT-P) questionnaires were administered and scored.
Thirty (49.18%) patients had BTO (BTO group), while 31 (50.82%) patients had BSO (BSO group) for advanced prostate cancer. On comparison of the two groups, there were no statistically significant differences in FACT-P scores at 1 month and 3 months. The subscale scores also showed no significant statistical difference except for the physical well-being score at 3 months post-orchiectomy, which was lower in the BSO group (P = 0.041). The average scores of Item P5 (I am able to feel like a man) which were used to assess the sex-role identity declined on an average over 3 months with no statistically significant difference on comparison of the two groups.
The QoL scores (FACT-P and FACT-G) assessed over 3 months post-orchiectomy did not differ on comparison of the BTO group and the BSO group. Performing a BSO in our region did not result in any psychological benefit when compared to performing a BTO.
与双侧睾丸全切术(BTO)相比,双侧睾丸包膜下切除术(BSO)据说在美学和心理满意度方面更佳。本研究比较了接受BTO和BSO的晚期前列腺癌男性的生活质量(QoL),重点关注他们对自身作为男性的自我认知或身份认同。
招募了61例选择双侧睾丸切除术的晚期前列腺癌患者。在睾丸切除术前、术后1个月和3个月,发放并计分前列腺癌的癌症治疗功能评估(FACT-P)问卷。
30例(49.18%)患者接受了BTO(BTO组),而31例(50.82%)患者接受了BSO(BSO组)用于治疗晚期前列腺癌。两组比较,术后1个月和3个月时FACT-P评分无统计学显著差异。除睾丸切除术后3个月时身体幸福感评分外,各子量表评分也无显著统计学差异,BSO组该评分较低(P = 0.041)。用于评估性别角色认同的P5项(我能够感觉自己像个男人)平均得分在3个月内下降,两组比较无统计学显著差异。
睾丸切除术后3个月评估的QoL评分(FACT-P和FACT-G)在BTO组和BSO组比较中无差异。在我们地区,与进行BTO相比,进行BSO并未带来任何心理益处。