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Thermal Stress and Nuclear Transport.
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FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Cell. 2018 Apr 19;173(3):720-734.e15. doi: 10.1016/j.cell.2018.03.056.
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Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004.
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Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell. 2018 Apr 19;173(3):693-705.e22. doi: 10.1016/j.cell.2018.03.003.
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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Cell. 2018 Apr 19;173(3):677-692.e20. doi: 10.1016/j.cell.2018.03.002.
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Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors.
Cell Rep. 2018 Mar 27;22(13):3660-3671. doi: 10.1016/j.celrep.2018.03.022.
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Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Cell. 2017 Oct 19;171(3):615-627.e16. doi: 10.1016/j.cell.2017.08.048. Epub 2017 Sep 21.
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The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease.
Biochem Soc Trans. 2016 Oct 15;44(5):1185-1200. doi: 10.1042/BST20160172.
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Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.
Nat Commun. 2016 Jun 23;7:11974. doi: 10.1038/ncomms11974.
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Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Mol Cell. 2015 Oct 15;60(2):231-41. doi: 10.1016/j.molcel.2015.09.006. Epub 2015 Oct 8.
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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
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