Zhang Dao Pei, Peng Yan Fang, Ma Qian Kun, Zhao Min, Zhang Huai Liang, Yin Suo
Department of Neurology, The First Affiliated Hospital of Henan University of CM, Zhengzhou, China.
Department of Neurology, People's Hospital of Zhengzhou Affiliated to Southern Medical University, Zhengzhou, China.
BMC Neurol. 2018 Apr 20;18(1):45. doi: 10.1186/s12883-018-1045-0.
Vertebrobasilar dolichoectasia (VBD) is a clinical entity associated with ischemic stroke, compression of cranial nerves or brainstem, and hydrocephalus. There have been relatively few studies following the progression of VBD in patients presenting with a variety of diverse clinical features.
Here, we report a case study of a male with progressive VBD who was followed from November 2012 to December 2016. The patient had diagnosed hypertension for several years and suffered from left peripheral facial paralysis, recurrent ischemic attacks in the brainstem and cerebellum, obstructive hydrocephalus and frequent pneumonia. A series of cranial CT and multi-modal MRI scans were performed to explore the brain imaging features of the patient during follow-up.
The presented case study suggests that aging, uncontrolled hypertension, arterial dissection and infection may contribute to the exacerbation of VBD and recurrent ischemic stroke.
椎基底动脉延长扩张症（VBD）是一种与缺血性中风、颅神经或脑干受压以及脑积水相关的临床病症。针对具有各种不同临床特征的患者，跟踪VBD进展的研究相对较少。
在此，我们报告一例男性进行性VBD的病例研究，该患者从2012年11月至2016年12月接受随访。该患者患有高血压数年，伴有左侧周围性面瘫、脑干和小脑反复缺血发作、梗阻性脑积水以及频繁肺炎。在随访期间进行了一系列头颅CT和多模态MRI扫描，以探究该患者的脑影像学特征。
本病例研究表明，衰老、未控制的高血压、动脉夹层和感染可能导致VBD加重及反复缺血性中风。
