Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Department of Biostatistics, Kyoto University School of Public Health, Kyoto, Japan.
Diabetes Res Clin Pract. 2018 Jul;141:26-34. doi: 10.1016/j.diabres.2018.04.006. Epub 2018 Apr 19.
To investigate the association between insulin resistance assessed by a homeostasis model and dietary habits.
Cross-sectional analysis using a community-based cohort, the Nagahama Prospective Cohort for Comprehensive Human Bioscience. Multiple linear regression analysis was performed with log HOMA-IR or log HOMA-β as the dependent variable and 20 dietary habits, tobacco smoking, medical history, family medical history of diabetes, age and BMI as the simultaneous independent variables in each sex separately.
Females (n = 2956) eating fish dishes every day had a HOMA-IR 0.90 times that of the reference group (P = 0.043). Females eating miso-soup every day had a HOMA-IR 0.95 times that of the reference group (P = 0.038). Males (n = 1371) eating vegetable dishes every day had a HOMA-IR 0.91 times that of the reference group (P = 0.003). Males eating egg dishes 4 to 5 times per week had a HOMA-IR 1.14 times that of the reference group (P = 0.011). Males eating fruits every day had a HOMA-IR 1.13 that of the reference group (P = 0.008).
Dietary habits associated with lower insulin resistance were eating fish dishes, miso soup or vegetable dishes every day and eating staple foods for dinner, egg dishes or fruits less frequently.
研究通过稳态模型评估的胰岛素抵抗与饮食习惯之间的关系。
使用基于社区的队列——长滨前瞻性综合人类生物科学队列进行横断面分析。分别对男性和女性，将 20 种饮食习惯、吸烟状况、既往病史、糖尿病家族史、年龄和 BMI 作为同时的独立变量，以 log HOMA-IR 或 log HOMA-β 为因变量进行多元线性回归分析。
女性（n=2956）每天吃鱼类菜肴者的 HOMA-IR 为参照组的 0.90 倍（P=0.043）。女性每天吃味噌汤者的 HOMA-IR 为参照组的 0.95 倍（P=0.038）。男性（n=1371）每天吃蔬菜菜肴者的 HOMA-IR 为参照组的 0.91 倍（P=0.003）。男性每周吃 4-5 次蛋类菜肴者的 HOMA-IR 为参照组的 1.14 倍（P=0.011）。男性每天吃水果者的 HOMA-IR 为参照组的 1.13 倍（P=0.008）。
与较低胰岛素抵抗相关的饮食习惯是每天食用鱼类菜肴、味噌汤或蔬菜菜肴，以及晚餐少吃主食、蛋类菜肴或水果。
