在程序性死亡受体 1 配体（PD-L1）抑制剂和化疗失败后，奥拉帕尼对 BRCA2 基因改变的尿路上皮癌有显著疗效。 - Suppr

Exceptional response to olaparib in BRCA2-altered urothelial carcinoma after PD-L1 inhibitor and chemotherapy failure.

作者信息

Necchi Andrea, Raggi Daniele, Giannatempo Patrizia, Alessi Alessandra, Serafini Gianluca, Colecchia Maurizio, Ali Siraj M, Chung Jon H

机构信息

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

出版信息

Eur J Cancer. 2018 Jun;96:128-130. doi: 10.1016/j.ejca.2018.03.021. Epub 2018 Apr 18.

DOI:10.1016/j.ejca.2018.03.021

PMID:29680362

Abstract

摘要

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Exceptional response to olaparib in BRCA2-altered urothelial carcinoma after PD-L1 inhibitor and chemotherapy failure.在程序性死亡受体 1 配体（PD-L1）抑制剂和化疗失败后，奥拉帕尼对 BRCA2 基因改变的尿路上皮癌有显著疗效。

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Exceptional response to olaparib in BRCA2-altered urothelial carcinoma after PD-L1 inhibitor and chemotherapy failure.

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