Mitchell Fiona, Henderson Hazel J, Gardner Faith
Tanyard and Muirkirk Medical Group, East Ayrshire, UK.
Department of Public Health, NHS Ayrshire and Arran, Ayr, UK.
BMJ Case Rep. 2018 Apr 21;2018:bcr-2017-223022. doi: 10.1136/bcr-2017-223022.
Three young women, aged 18-24 years, presented to general practice with signs and symptoms of exertional rhabdomyolysis in 2016. All attended the same gym and had undertaken an intensive physical workout. Presenting symptoms were severe muscle pain and swelling, significantly reduced range of motion in affected muscles and, in two cases, dark-coloured urine. One case had presented to the out-of-hours service 4 months previously with similar symptoms but rhabdomyolysis was not considered, although retrospective history taking suggests that was the likely diagnosis. All three women were admitted to hospital, treated with intravenous fluids and discharged between 1 and 6 days later. All made a full recovery with no renal sequelae. The cases were questioned about potential risk factors, and the only commonality was unaccustomed strenuous exercise.
2016年,三名年龄在18至24岁之间的年轻女性因运动性横纹肌溶解症的体征和症状前往全科诊所就诊。她们都在同一家健身房锻炼,并进行了高强度的体能训练。出现的症状包括严重的肌肉疼痛和肿胀、受影响肌肉的活动范围明显减小,以及两例出现深色尿液。其中一名患者在4个月前曾因类似症状向非工作时间服务机构就诊,但当时未考虑横纹肌溶解症,不过回顾病史表明当时可能就是该诊断。所有三名女性均入院治疗,接受了静脉输液,1至6天后出院。她们均完全康复,没有出现肾脏后遗症。对这些病例询问了潜在风险因素,唯一的共同点是不习惯的剧烈运动。