The Fenway Institute, Fenway Health, Boston, MA, 02118, USA.
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
AIDS Behav. 2018 Sep;22(9):2868-2876. doi: 10.1007/s10461-018-2116-3.
Cigarette smoking is particularly harmful for sexual minority men living with HIV. This study aimed to find benefits of quitting by examining relationships between smoking and sustained HIV RNA suppression, recent CD4 count, ART medication adherence, and engagement in HIV medical care. Sexual minority men (n = 346), former or current smokers, received HIV care at a community health center. Survey responses were combined with electronic health record data in adjusted regression models. Most patients were Caucasian (87%) and 148 (46%) had incomes below the poverty level and 80% had sustained HIV RNA suppression. Compared to current smokers, former smokers had increased odds of sustaining HIV RNA suppression (OR 1.89; 95% CI 1.02-3.48) of reporting > 90% adherence (OR 2.25; 95% CI 1.21-4.17), and were less likely to miss appointments (OR 0.37; 95% CI 0.17-0.82). Heavier smokers (OR 0.36; 95% CI 0.17-0.77) and patients who smoked the longest (OR 0.31; 95% CI 0.14-0.68) had reduced odds of sustaining HIV RNA suppression. Smoking assessment, treatment, and referral could augment HIV outcomes for sexual minority men with HIV.
吸烟对感染艾滋病毒的性少数群体男性尤其有害。本研究旨在通过检查吸烟与持续的 HIV RNA 抑制、最近的 CD4 计数、抗逆转录病毒治疗药物依从性以及参与艾滋病毒医疗保健之间的关系，来寻找戒烟的好处。性少数群体男性（n=346），前或现吸烟者，在社区卫生中心接受艾滋病毒护理。调查答复与电子健康记录数据相结合，纳入调整后的回归模型。大多数患者为白种人（87%），148 人（46%）收入低于贫困线，80%的人持续抑制 HIV RNA。与当前吸烟者相比，曾经吸烟者持续抑制 HIV RNA 的可能性更高（OR 1.89；95%CI 1.02-3.48），报告>90%的依从性（OR 2.25；95%CI 1.21-4.17）的可能性更高，并且不太可能错过预约（OR 0.37；95%CI 0.17-0.82）。吸烟量较大的吸烟者（OR 0.36；95%CI 0.17-0.77）和吸烟时间最长的患者（OR 0.31；95%CI 0.14-0.68）持续抑制 HIV RNA 的可能性降低。对性少数群体男性进行吸烟评估、治疗和转介可以改善他们的艾滋病毒治疗效果。
