Live Birth after Rescue Maturation-intracytoplasmic Sperm Injection in Type 1 Diabetes, Polycystic Ovary Syndrome Patient Using Clomiphene-antagonist Protocol.
作者信息
Sankari Samundi, Elanchezhian M, Selvamani Divya, Nagarajan M, Gopikrishnan D
机构信息
Department of IVF and Genetics, Srushti Fertility Centre and Women's Hospital, Chennai, Tamil Nadu, India.
出版信息
J Hum Reprod Sci. 2018 Jan-Mar;11(1):75-78. doi: 10.4103/jhrs.JHRS_65_17.
Abstract
Infertility in patients with polycystic ovary syndrome (PCOS) associated with diabetes leads to challenging situations seeking alternative treatments. maturation (IVM) followed by intracytoplasmic sperm injection (ICSI) could overcome the challenges with promising pregnancies in such patients. In the treatment of a 32-year-old diabetic woman who also had PCOS, single immature oocyte was retrieved. Rescue IVM followed by ICSI yielded a grade 1 day 3 embryo which on transferring resulted in pregnancy and a healthy infant was delivered. Rescue IVM-ICSI could help in achieving pregnancy and live birth. Stimulation involving clomiphene and gonadotropin-releasing hormone antagonist is an effective and patient-friendly protocol for women with PCOS and diabetes and also for poor responders.
摘要
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