血管性痴呆中的神经精神症状：流行病学和临床方面。
Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects.
作者信息
Santos Marcelo Antônio Oliveira, Bezerra Lucas Soares, Correia Carolina da Cunha, Bruscky Igor Silvestre
机构信息
Director of the Epidemiology and Cardiology Research Group, Federal University of Pernambuco, Recife, PE, Brazil. Medical Student at Mauricio de Nassau University, Recife, PE, Brazil.
Full Professor of Neurology, Maurício de Nassau University, PE, Brazil.
出版信息
Dement Neuropsychol. 2018 Jan-Mar;12(1):40-44. doi: 10.1590/1980-57642018dn12-010006.
UNLABELLED
Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases.
OBJECTIVE
To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia.
METHODS
A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS).
RESULTS
81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02).
CONCLUSION
Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS.
未标注
痴呆是一组异质性有机神经退行性疾病的统称。脑血管病因占病例的20%。
目的
描述在一家痴呆转诊医院中，年龄>60岁的血管性痴呆（VD）或混合性痴呆（MxD）患者的临床和流行病学特征。
方法
2014年至2017年进行了一项描述性回顾性研究，纳入患有VA或MxD的老年个体（≥60岁）。排除患有其他形式痴呆或正在使用模拟认知障碍药物的患者。使用12项神经精神科问卷评估神经精神症状（NPS）。
结果
81.1%的患者出现NPS，只有15%有两种或更多症状。冷漠是最常见的NPS（56.6%）。CDR评分为1或2与NPS之间存在关联（OR = 6.16，95% CI：1.36 - 27.9，p = 0.02）。
结论
大多数患者有单一症状，主要是冷漠。轻度至中度痴呆与NPS之间存在关联。
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