《神经精神科问卷：编制与应用》
The Neuropsychiatric Inventory: Development and Applications.
作者信息
Cummings Jeffrey
机构信息
Department of Brain Health, School of integrated Health Sciences, UNLV, Las Vegas, NV, USA.
Lou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, NV, USA.
出版信息
J Geriatr Psychiatry Neurol. 2020 Mar;33(2):73-84. doi: 10.1177/0891988719882102.
Abstract
REASONS FOR THE STUDY
The Neuropsychiatric Inventory (NPI) has been used for studies of neuropsychiatric symptoms in neurodegenerative disorders for the past 25 years. This article reviews the history of the development and application of the NPI.
MAIN FINDINGS
The NPI consists of 10 (or 12) items that are assayed with questions, subquestions, and ratings of frequency and severity. The NPI has been shown to be valid and reliable. The NPI has been translated into approximately 40 languages; it has 4 of versions designed for different clinical applications. The NPI studies show contrasting profiles of behavioral symptoms in different neurologic disorders. The NPI has been used in approximately 350 clinical trials. In economic studies, the NPI captures the cost of behavioral symptoms in dementias.
PRINCIPLE CONCLUSIONS
The NPI is a useful instrument for capturing behavioral changes in Alzheimer disease and other neurodegenerative disorders.
摘要
研究目的
在过去25年中，神经精神科问卷（NPI）一直用于神经退行性疾病的神经精神症状研究。本文回顾了NPI的发展和应用历史。
主要发现
NPI由10项（或12项）条目组成，通过问题、子问题以及频率和严重程度评分进行测定。NPI已被证明有效且可靠。NPI已被翻译成约40种语言；它有4种针对不同临床应用设计的版本。NPI研究显示了不同神经系统疾病中行为症状的对比情况。NPI已用于约350项临床试验。在经济学研究中，NPI可获取痴呆症行为症状的成本。
主要结论
NPI是一种用于捕捉阿尔茨海默病和其他神经退行性疾病行为变化的有用工具。
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