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再次接受甲状腺手术的复发性甲状腺肿患者喉返神经移位情况

Displacement of the Recurrent Laryngeal Nerve in Patients with Recurrent Goiter Undergoing Redo Thyroid Surgery.

作者信息

Gurleyik Emin, Cetin Fuat, Dogan Sami, Yekenkurul Erman, Onsal Ufuk, Gursoy Fatih, Ipor Alper

机构信息

Department of Surgery, Medical Faculty, Düzce University, Düzce, Turkey.

出版信息

J Thyroid Res. 2018 Feb 28;2018:4763712. doi: 10.1155/2018/4763712. eCollection 2018.

DOI:10.1155/2018/4763712
PMID:29682274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5851157/
Abstract

Thyroid reoperations are surgically challenging because of scarring and disturbances in the anatomy of the recurrent laryngeal nerve (RLN). This study was conducted on 49 patients who underwent redo surgery. 61 RLNs were identified and completely exposed. Their functional integrity was evaluated using intraoperative nerve monitoring (IONM). Indications for secondary surgery, anatomical changes secondary to recurrent goiter mass and prior surgery, and results of IONM were studied. Frequent indications for redo surgery were multinodular goiter (MNG) in 19 (38.8%) and results of cytology in 14 (28.5%) patients. The mean time interval between primary and redo thyroid surgery was 23.4 years. We laterally approached 41 (67.2%) thyroid lobes between the sternocleidomastoid and sternohyoid muscles. 16 (26.2%) RLNs were found to be adherent to the lateral surface of the corresponding thyroid lobe. The functional integrity of all RLNs was confirmed by IONM. The remnant thyroid tissue can then lead to goiter recurrence requiring secondary surgery after a long period of time. The indications for redo surgery were similar to primary cases. Lateral displacement of the RLN which is adherent to the lateral surface of recurrent goiter mass is common anatomic variation. Thyroid reoperations based on awareness of anatomical disturbances can be performed safely by an experienced surgeon with support of ancillary electrophysiological technology.

摘要

由于瘢痕形成和喉返神经(RLN)解剖结构紊乱,甲状腺再次手术具有手术挑战性。本研究对49例行再次手术的患者进行。共识别并完全暴露了61条RLN。使用术中神经监测(IONM)评估其功能完整性。研究了二次手术的指征、复发性甲状腺肿肿块及既往手术导致的解剖学变化以及IONM的结果。再次手术的常见指征为19例(38.8%)的多结节性甲状腺肿(MNG)和14例(28.5%)患者的细胞学结果。初次甲状腺手术与再次手术之间的平均时间间隔为23.4年。我们在胸锁乳突肌和胸骨舌骨肌之间从外侧入路处理了41个(67.2%)甲状腺叶。发现16条(26.2%)RLN附着于相应甲状腺叶的外侧表面。所有RLN的功能完整性均通过IONM得到确认。残留的甲状腺组织可能导致甲状腺肿复发,需要在很长一段时间后进行二次手术。再次手术的指征与初次病例相似。附着于复发性甲状腺肿肿块外侧表面的RLN发生侧向移位是常见的解剖变异。经验丰富的外科医生在辅助电生理技术的支持下,基于对解剖学紊乱的认识,可以安全地进行甲状腺再次手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf83/5851157/267fb7a5894b/JTR2018-4763712.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf83/5851157/5a2bf6e9f48f/JTR2018-4763712.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf83/5851157/267fb7a5894b/JTR2018-4763712.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf83/5851157/5a2bf6e9f48f/JTR2018-4763712.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf83/5851157/267fb7a5894b/JTR2018-4763712.002.jpg

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A meta-analysis of intraoperative neuromonitoring of recurrent laryngeal nerve palsy during thyroid reoperations.甲状腺再次手术中喉返神经麻痹术中神经监测的荟萃分析。
Clin Endocrinol (Oxf). 2017 Nov;87(5):572-580. doi: 10.1111/cen.13379. Epub 2017 Jul 13.
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Intermittent neural monitoring of the recurrent laryngeal nerve in surgery for recurrent goiter.
系统评价与荟萃分析:喉返神经变异及其在手术和颈部疾病中的意义,采用解剖学质量保证(AQUA)清单
Life (Basel). 2023 Apr 24;13(5):1077. doi: 10.3390/life13051077.
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Frequency and Type of Thyroid Carcinoma in Patients With Multinodular Goiter.多结节性甲状腺肿患者甲状腺癌的发病率及类型
Cureus. 2023 Apr 21;15(4):e37921. doi: 10.7759/cureus.37921. eCollection 2023 Apr.
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Visual and electrophysiological identification of the external branch of superior laryngeal nerve in redo thyroid surgery compared with primary thyroid surgery.与初次甲状腺手术相比,再次甲状腺手术中喉上神经外支的视觉和电生理识别
Ann Surg Treat Res. 2019 Jun;96(6):269-274. doi: 10.4174/astr.2019.96.6.269. Epub 2019 May 29.
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