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巨大囊性多结节性甲状腺肿伴胸骨后延伸的治疗。病例报告。

Management of a huge cystic multi-nodular goiter with retro-sternal extension. Case report.

作者信息

Shabhay Ahmed Ali, Massaga Fabian Anaclet, Mwami Amri Salim, Ngwira Jonathan Joseph, Ndyamkama Domician Sospeter, Shabhay Zarina Ali

机构信息

Military Hospital Mwanza, P. O Box 589, Mwanza, Tanzania.

Bugando Medical Center, P. O Box 1370, Mwanza, Tanzania.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110931. doi: 10.1016/j.ijscr.2025.110931. Epub 2025 Jan 27.

DOI:10.1016/j.ijscr.2025.110931
PMID:39874800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11808684/
Abstract

INTRODUCTION AND IMPORTANCE

Surgical management of huge multi-nodular goiters present clinical and surgical management dilemma among practicing surgeons. Thyroidectomies pose huge risk potential when performed by relatively inexperienced and junior operators.

CASE PRESENTATION

We present a case of a 40-year-old lady who had presented at our center with a ten-year history of painless anterior neck swelling. She was diagnosed with a multinodular goiter and underwent total thyroidectomy.

CLINICAL DISCUSSION

Success of thyroid surgery depends upon operators' skill, training, experience, specialty and "thyroid volume surgery" index. Huge thyroid gland surgeries even to competent performers presents with challenges. The choice of type of thyroidectomy is still a dilemma among practicing surgeons. The employment of total thyroidectomy presents with risks of recurrent laryngeal nerve injury and parathyroid glands injury due to the nature of the radical dissection. However, it offers the advantage of complete resection of the diseased gland and alienates the chances of recurrence.

CONCLUSION

It is the authors' opinion that total thyroidectomy for huge multi-nodular goiters is a safe procedure when performed by trained skilled surgeons and should be the standard for the management of multinodular goiters.

摘要

引言与重要性

巨大结节性甲状腺肿的外科治疗给外科医生在临床和手术管理方面带来了两难困境。由经验相对不足的初级手术医生进行甲状腺切除术时存在巨大的潜在风险。

病例介绍

我们报告一例40岁女性患者,她因无痛性颈前肿胀10年就诊于我院。她被诊断为结节性甲状腺肿并接受了全甲状腺切除术。

临床讨论

甲状腺手术的成功取决于手术医生的技能、培训、经验、专业以及“甲状腺体积手术”指数。即使对于经验丰富的手术医生,巨大甲状腺手术也面临挑战。在执业外科医生中,甲状腺切除术的类型选择仍然是一个难题。由于根治性解剖的性质,全甲状腺切除术存在喉返神经损伤和甲状旁腺损伤的风险。然而,它具有完全切除病变腺体的优势,并消除了复发的可能性。

结论

作者认为,对于巨大结节性甲状腺肿,由训练有素、技术熟练的外科医生进行全甲状腺切除术是一种安全的手术方式,应成为结节性甲状腺肿治疗的标准方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/20c3bcdc0341/gr8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/20c3bcdc0341/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/a71a3c95a80a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/555be7c2df84/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/4879e06c0fd7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/d184ee6ef52c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/c1e15d7e072e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/db58fc2a90da/gr6.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd8/11808684/20c3bcdc0341/gr8.jpg

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本文引用的文献

1
The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
2
The volume and outcome relationship for thyroidectomy in England.英国甲状腺切除术的数量与结果关系。
Langenbecks Arch Surg. 2021 Sep;406(6):1999-2010. doi: 10.1007/s00423-021-02223-8. Epub 2021 Jun 9.
3
A two kilograms euthyroid goiter in Singida Regional Referral Hospital, Central Tanzania: Case report.
坦桑尼亚中部辛吉达地区转诊医院的一例两千克甲状腺功能正常的甲状腺肿:病例报告。
Int J Surg Case Rep. 2020;77:430-433. doi: 10.1016/j.ijscr.2020.11.010. Epub 2020 Nov 4.
4
Patient, thyroid, and surgeon related factors that make thyroidectomy difficult-cohort study.导致甲状腺切除术困难的患者、甲状腺及外科医生相关因素——队列研究
Ann Med Surg (Lond). 2019 Nov 23;49:14-18. doi: 10.1016/j.amsu.2019.11.010. eCollection 2020 Jan.
5
Displacement of the Recurrent Laryngeal Nerve in Patients with Recurrent Goiter Undergoing Redo Thyroid Surgery.再次接受甲状腺手术的复发性甲状腺肿患者喉返神经移位情况
J Thyroid Res. 2018 Feb 28;2018:4763712. doi: 10.1155/2018/4763712. eCollection 2018.
6
Multinodular goiter in children: treatment controversies.儿童结节性甲状腺肿:治疗争议
J Pediatr Endocrinol Metab. 2017 Aug 28;30(8):847-850. doi: 10.1515/jpem-2016-0368.
7
Thyroid Disorders in Central Ghana: The Influence of 20 Years of Iodization.加纳中部地区的甲状腺疾病:二十年碘化作用的影响
J Thyroid Res. 2017;2017:7843972. doi: 10.1155/2017/7843972. Epub 2017 Jul 4.
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A Fifteen Year Experience of Total Thyroidectomy for the Management of Simple Multinodular Goitres in a Low Medium Income Country.在一个中低收入国家,甲状腺全切除术治疗单纯性结节性甲状腺肿的15年经验。
S Afr J Surg. 2016 Nov;54(4):40-45.
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Total Thyroidectomy for Benign Thyroid Diseases: What is the Price to be Paid?良性甲状腺疾病的全甲状腺切除术:需要付出什么代价?
J Clin Diagn Res. 2016 Jun;10(6):PC04-7. doi: 10.7860/JCDR/2016/18733.7991. Epub 2016 Jun 1.
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Medicine (Baltimore). 2016 Jul;95(28):e4194. doi: 10.1097/MD.0000000000004194.