Bruckstein A H
Department of Medicine, St. Vincent's Medical Center of Richmond, Staten Island, NY 10310.
Postgrad Med. 1988 Jul;84(1):85-94. doi: 10.1080/00325481.1988.11700336.
Because safe, effective treatment for established viral hepatitis is not available, physicians need to be acquainted with recent advances in prophylaxis. Immune globulin (Gamastan, Gammar) is used for both preexposure and postexposure prophylaxis of hepatitis A, and side effects are rare. Two vaccines (Heptavax-B, Recombivax HB) are licensed for hepatitis B, one is a plasma-derived vaccine, the other a yeast-recombinant vaccine. Indirectly, these also control hepatitis D (delta agent), which needs hepatitis B virus to develop.
由于目前尚无针对已确诊病毒性肝炎的安全、有效治疗方法,医生需要了解预防方面的最新进展。免疫球蛋白(伽马球蛋白)可用于甲型肝炎暴露前和暴露后的预防,且副作用罕见。有两种疫苗(乙肝疫苗,重组酵母乙肝疫苗)被批准用于预防乙型肝炎,一种是血浆源性疫苗,另一种是酵母重组疫苗。间接地,这些疫苗也可控制丁型肝炎(丁型肝炎病毒),因为丁型肝炎需要乙型肝炎病毒才能发展。