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Organoids reveal cancer dynamics.

作者信息

Kuo Calvin J, Curtis Christina

出版信息

Nature. 2018 Apr;556(7702):441-442. doi: 10.1038/d41586-018-03841-x.

DOI:10.1038/d41586-018-03841-x
PMID:29686366
Abstract
摘要

相似文献

1
Organoids reveal cancer dynamics.类器官揭示癌症动态。
Nature. 2018 Apr;556(7702):441-442. doi: 10.1038/d41586-018-03841-x.
2
[Normal organoids and their applications in cancer research].[正常类器官及其在癌症研究中的应用]
Bull Cancer. 2022 Jan;109(1):58-64. doi: 10.1016/j.bulcan.2021.11.004. Epub 2021 Dec 10.
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Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms.胰腺导管内乳头状黏液性肿瘤衍生类器官的分子特征。
J Pathol. 2020 Nov;252(3):252-262. doi: 10.1002/path.5515. Epub 2020 Sep 19.
4
Three-Dimensional Organoids in Cancer Research: The Search for the Holy Grail of Preclinical Cancer Modeling.三维类器官在癌症研究中的应用:对临床前癌症建模圣杯的探索。
OMICS. 2018 Dec;22(12):733-748. doi: 10.1089/omi.2018.0172.
5
Organoids in lung cancer: A teenager with infinite growth potential.类器官在肺癌中的应用:拥有无限生长潜能的青少年。
Lung Cancer. 2022 Oct;172:100-107. doi: 10.1016/j.lungcan.2022.08.006. Epub 2022 Aug 11.
6
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.早期结直肠癌类器官培养物揭示了独特且罕见的遗传特征。
Gut. 2020 Dec;69(12):2165-2179. doi: 10.1136/gutjnl-2019-320019. Epub 2020 Mar 26.
7
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.三维类器官揭示食管和口咽鳞状细胞癌细胞的治疗抵抗性。
Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):73-91. doi: 10.1016/j.jcmgh.2018.09.003. eCollection 2019.
8
Organoids of epithelial ovarian cancer as an emerging preclinical in vitro tool: a review.上皮性卵巢癌类器官作为一种新兴的临床前体外工具的研究进展:综述
J Ovarian Res. 2019 Nov 8;12(1):105. doi: 10.1186/s13048-019-0577-2.
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From Cancer to Immune Organoids: Innovative Preclinical Models to Dissect the Crosstalk between Cancer Cells and the Tumor Microenvironment.从癌症到免疫类器官:创新的临床前模型来剖析癌细胞与肿瘤微环境的相互作用。
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Image-based profiling and deep learning reveal morphological heterogeneity of colorectal cancer organoids.基于图像的分析和深度学习揭示了结直肠癌细胞球体的形态异质性。
Comput Biol Med. 2024 May;173:108322. doi: 10.1016/j.compbiomed.2024.108322. Epub 2024 Mar 26.

引用本文的文献

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Transforming cancer treatment: integrating patient-derived organoids and CRISPR screening for precision medicine.变革癌症治疗:整合患者来源的类器官和CRISPR筛选以实现精准医学
Front Pharmacol. 2025 Mar 25;16:1563198. doi: 10.3389/fphar.2025.1563198. eCollection 2025.
2
Liver organoids: a promising three-dimensional model for insights and innovations in tumor progression and precision medicine of liver cancer.肝类器官:肿瘤进展和肝癌精准医学中洞察和创新的有前途的三维模型。
Front Immunol. 2023 Jun 2;14:1180184. doi: 10.3389/fimmu.2023.1180184. eCollection 2023.
3
The pivotal application of patient-derived organoid biobanks for personalized treatment of gastrointestinal cancers.
患者来源的类器官生物样本库在胃肠道癌症个性化治疗中的关键应用。
Biomark Res. 2022 Oct 8;10(1):73. doi: 10.1186/s40364-022-00421-0.
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Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today?类器官作为恶性胸膜间皮瘤精准医学的模型:我们目前进展如何?
Cancers (Basel). 2022 Aug 2;14(15):3758. doi: 10.3390/cancers14153758.
5
Tumor organoids: synergistic applications, current challenges, and future prospects in cancer therapy.肿瘤类器官:在癌症治疗中的协同应用、当前挑战与未来前景。
Cancer Commun (Lond). 2021 Dec;41(12):1331-1353. doi: 10.1002/cac2.12224. Epub 2021 Oct 29.
6
Challenges for the Applications of Human Pluripotent Stem Cell-Derived Liver Organoids.人多能干细胞衍生肝类器官应用面临的挑战。
Front Cell Dev Biol. 2021 Oct 1;9:748576. doi: 10.3389/fcell.2021.748576. eCollection 2021.
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A Patient-Derived Organoid-Based Radiosensitivity Model for the Prediction of Radiation Responses in Patients with Rectal Cancer.一种基于患者来源类器官的放射敏感性模型,用于预测直肠癌患者的放射反应
Cancers (Basel). 2021 Jul 27;13(15):3760. doi: 10.3390/cancers13153760.
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Trends in the development of human stem cell-based non-animal drug testing models.基于人类干细胞的非动物药物测试模型的发展趋势。
Korean J Physiol Pharmacol. 2020 Nov 1;24(6):441-452. doi: 10.4196/kjpp.2020.24.6.441.
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Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential.肿瘤类器官的形态表型分类作为药物暴露和渗透潜力的指标。
PLoS Comput Biol. 2019 Jul 16;15(7):e1007214. doi: 10.1371/journal.pcbi.1007214. eCollection 2019 Jul.
10
Polytherapy and Targeted Cancer Drug Resistance.联合治疗与靶向抗癌耐药性
Trends Cancer. 2019 Mar;5(3):170-182. doi: 10.1016/j.trecan.2019.02.003. Epub 2019 Feb 26.