先天性心脏病患儿心脏健康的早期生活环境与社会决定因素
Early life environment and social determinants of cardiac health in children with congenital heart disease.
作者信息
Wong Peter, Denburg Avram, Dave Malini, Levin Leo, Morinis Julia Orkin, Suleman Shazeen, Wong Jonathan, Ford-Jones Elizabeth, Moore Aideen M
机构信息
Department of Paediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario.
出版信息
Paediatr Child Health. 2018 Apr;23(2):92-95. doi: 10.1093/pch/pxx146. Epub 2017 Nov 2.
Abstract
Congenital heart disease is a significant cause of infant mortality. Epidemiology and social context play a crucial role in conditioning disease burden and modulating outcomes, while diagnosis and treatment remain resource intensive. This review will address the role of social demographics, environmental exposure, epigenetics and nutrition in the aetiology of congenital heart disease. We then discuss the determinant effect of social factors on the provision and outcomes of care for congenital heart disease and implications for practice. It is our hope that enhanced knowledge of the intersection of social determinants of health and congenital heart disease will facilitate effective preventative strategies at the individual and population levels to optimize heart health outcomes across the life course.
摘要
先天性心脏病是婴儿死亡的一个重要原因。流行病学和社会背景在决定疾病负担和调节预后方面起着关键作用，而诊断和治疗仍然需要大量资源。本综述将探讨社会人口统计学、环境暴露、表观遗传学和营养在先天性心脏病病因学中的作用。然后，我们将讨论社会因素对先天性心脏病护理提供和预后的决定性影响及其对实践的意义。我们希望，加强对健康社会决定因素与先天性心脏病交叉领域的认识，将有助于在个体和人群层面制定有效的预防策略，以优化整个生命过程中的心脏健康结果。
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