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脑穿通畸形囊肿:成人新发癫痫的罕见病因。

Porencephalic cyst: a rare cause of new-onset seizure in an adult.

作者信息

Qureshi Anam, Jehangir Asad, York Eugene P

机构信息

Department of Internal Medicine, Reading Hospital - Tower Health, West Reading, PA, USA.

出版信息

J Community Hosp Intern Med Perspect. 2018 Apr 17;8(2):92-93. doi: 10.1080/20009666.2018.1454788. eCollection 2018.

DOI:10.1080/20009666.2018.1454788
PMID:29686797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5906768/
Abstract

We present a case of a 56-year-old male with a history of perinatal intracerebral hemorrhage who presented to the emergency department after a witnessed new-onset generalized tonic-clonic seizure. Computerized tomography and magnetic resonance imaging of the head revealed a large frontal lobe porencephalic cyst, with encephalomalacia in the right parietal lobe and temporal lobe (the patient did not have any prior cranial imaging). The patient has subsequently remained seizure-free on levetiracetam. Porencephalic cyst is a rare condition of cerebrospinal fluid accumulation in the brain parenchyma that is usually related to perinatal vascular events. These cysts can have a wide array of clinical presentations. This can include partial or generalized seizures, which are usually managed by antiepileptics.

摘要

我们报告一例56岁男性患者,有围产期脑出血病史,在目睹其新发全身性强直阵挛发作后被送往急诊科。头部计算机断层扫描和磁共振成像显示一个巨大的额叶脑穿通性囊肿,右侧顶叶和颞叶存在脑软化(患者此前未进行过任何颅脑影像学检查)。该患者随后服用左乙拉西坦后未再发作。脑穿通性囊肿是一种罕见的脑脊液在脑实质内积聚的疾病,通常与围产期血管事件有关。这些囊肿可有多种临床表现。这包括部分性或全身性发作,通常用抗癫痫药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c3/5906768/15d24328786d/ZJCH_A_1454788_F0002_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c3/5906768/08d4efc8e00a/ZJCH_A_1454788_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c3/5906768/15d24328786d/ZJCH_A_1454788_F0002_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c3/5906768/08d4efc8e00a/ZJCH_A_1454788_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c3/5906768/15d24328786d/ZJCH_A_1454788_F0002_B.jpg

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本文引用的文献

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2
Neuroepidemiology of Porencephaly, Schizencephaly, and Hydranencephaly in Miyagi Prefecture, Japan.日本宫城县脑穿通畸形、脑裂畸形和积水性无脑畸形的神经流行病学
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The differences in epileptic characteristics in patients with porencephaly and schizencephaly.
癫痫作为一名儿童中与胼胝体发育不全相关的神经胶质囊肿的一种表现形式。
Case Rep Radiol. 2021 Jan 21;2021:6675071. doi: 10.1155/2021/6675071. eCollection 2021.
4
Pregnancy in an Asymptomatic Woman with Porencephalic and Arachnoid Cysts.一名患有脑穿通畸形囊肿和蛛网膜囊肿的无症状女性怀孕
Case Rep Obstet Gynecol. 2020 Nov 18;2020:8885114. doi: 10.1155/2020/8885114. eCollection 2020.
5
Intraparenchymal hemorrhage and cerebral venous thrombosis in an adult with congenital porencephalic cyst presenting for generalized tonic-clonic seizures.一名患有先天性脑穿通畸形囊肿的成人出现全身强直阵挛性癫痫发作,并发脑实质内出血和脑静脉血栓形成。
Radiol Case Rep. 2019 Nov 12;15(1):95-99. doi: 10.1016/j.radcr.2019.10.028. eCollection 2020 Jan.
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Increased Susceptibility to Postoperative PCA Morphine-Induced Respiratory Depression in a Patient with an Undiagnosed Traumatic Porencephalic Cyst - A Case Report.一名未确诊创伤性脑穿通囊肿患者术后PCA吗啡诱导的呼吸抑制易感性增加——病例报告
J Crit Care Med (Targu Mures). 2019 May 13;5(2):66-70. doi: 10.2478/jccm-2019-0011. eCollection 2019 Apr.
孔洞脑和脑裂畸形患者癫痫特征的差异。
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