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采用同位素指纹图谱和代谢组学分析结合的方法鉴定锯棕榈(Serenoa repens)提取物。

Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts.

机构信息

Experiment and Technological Services Department, Technology Transfer Centre, Fondazione Edmund Mach (FEM), Via E. Mach 1, 38010 San Michele all'Adige, Italy.

Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach (FEM), Via E. Mach 1, 38010 San Michele all'Adige, Italy.

出版信息

Fitoterapia. 2018 Jun;127:15-19. doi: 10.1016/j.fitote.2018.04.011. Epub 2018 Apr 22.

DOI:10.1016/j.fitote.2018.04.011
PMID:29689331
Abstract

Saw palmetto (Serenoa repens, SP) is the most expensive oil source of the pharmaceutical and healthfood market, and its high cost and recurrent shortages have spurred the development of designer blends of fatty acids to mimic its phytochemical profile and fraudulently comply with the current authentication assays. To detect this adulteration, the combined use of isotopic fingerprint and omic analysis has been investigated, using Principal Component Analysis (PCA) to handle the complex databases generated by these techniques and to identify the possible source of the adulterants. Surprisingly, the presence of fatty acids of animal origin turned out to be widespread in commercial samples of saw palmetto oil.

摘要

锯棕榈(Serenoa repens,SP)是医药和保健品市场上最昂贵的油源,其高昂的成本和经常出现的短缺促使人们开发出脂肪酸的设计混合物来模拟其植物化学成分,并伪造符合当前鉴定方法的产品。为了检测这种掺假行为,已经研究了同位素指纹图谱和组学分析的联合使用,使用主成分分析(PCA)来处理这些技术生成的复杂数据库,并确定掺假剂的可能来源。令人惊讶的是,动物来源的脂肪酸在商业锯棕榈油样本中普遍存在。

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