Huang Z F, Wang Z F, Li C H, Hao D, Lan J
Department of Prosthodontics, School of Stomatology, Shandong University & Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan 250012, China.
Department of Pediatric Dentistry, School of Stomatology, Shandong University & Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan 250012, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2018 Apr 9;53(4):264-270. doi: 10.3760/cma.j.issn.1002-0098.2018.04.010.
To investigate the osseointegration of a novel coating-plasma-sprayed zirconia in dental implant. Zirconia coating on non-thread titanium implant was prepared using plasma spraying, the implant surface morphology, surface roughness and wettability were measured. , zirconia coated implants were inserted in rabbit tibia and animals were respectively sacrificed at 2, 4, 8 and 12 weeks after implantation. The bond strength between implant and bone was measured by push-out test. The osseointegration was observed by scanning electron microscopy (SEM), micro CT and histological analyses. Quantified parameters including removal torque, and bone-implant contact (BIC) percentage were calculated. The surface roughness (1.6 µm) and wettability (54.6°) of zirconia coated implant was more suitable than those of titanium implant (0.6 µm and 74.4°) for osseointegration. At 12 weeks, the push-out value of zirconia coated implant and titanium implant were (64.9±3.0) and (50.4±2.9) N, and BIC value of these two groups were (54.7±3.6)% and (41.5±3.6)%. All these differences had statistical significance. The surface characters of zirconia coated implant were more suitable for osseointegration and present better osseointegration than smooth titanium implant , especially at early stage.
为研究新型涂层——等离子喷涂氧化锆在牙种植体中的骨结合情况。采用等离子喷涂法在无螺纹钛种植体上制备氧化锆涂层，测量种植体表面形态、表面粗糙度和润湿性。将氧化锆涂层种植体植入兔胫骨，分别在植入后2、4、8和12周处死动物。通过推出试验测量种植体与骨之间的结合强度。通过扫描电子显微镜（SEM）、显微CT和组织学分析观察骨结合情况。计算包括去除扭矩和骨-种植体接触（BIC）百分比在内的量化参数。氧化锆涂层种植体的表面粗糙度（1.6 µm）和润湿性（54.6°）比钛种植体（0.6 µm和74.4°）更适合骨结合。在12周时，氧化锆涂层种植体和钛种植体的推出值分别为（64.9±3.0）和（50.4±2.9）N，两组的BIC值分别为（54.7±3.6）%和（41.5±3.6）%。所有这些差异均具有统计学意义。氧化锆涂层种植体的表面特性更适合骨结合，并且比光滑钛种植体具有更好的骨结合，尤其是在早期阶段。
