Department of Oral Anatomy, Dental Research Institute and School of Dentistry, Seoul National University, Seoul, Korea.
Clin Oral Implants Res. 2013 May;24(5):586-91. doi: 10.1111/j.1600-0501.2012.02468.x. Epub 2012 Apr 4.
To evaluate osseointegration in rabbit tibiae and to investigate surface characteristics of novel zirconia implants made by powder injection molding (PIM) technique, using molds with and without roughened inner surfaces.
A total of 20 rabbits received three types of external hex implants with identical geometry on the tibiae: machined titanium implants, PIM zirconia implants without mold etching, and PIM zirconia implants with mold etching. Surface characteristics of the three types of implant were evaluated. Removal torque tests and histomorphometric analyses were performed.
The roughness of PIM zirconia implants was higher than that of machined titanium implants. The PIM zirconia implants exhibited significantly higher bone-implant contact and removal torque values than the machined titanium implants (P < 0.001). The PIM zirconia implants using roughened mold showed significantly higher removal torque values than PIM zirconia implants without using roughened mold (P < 0.001).
It is concluded that the osseointegration of PIM zirconia implant is promising and PIM using roughened mold etching technique can produce substantially rough surfaces on zirconia implants.
评估兔胫骨中的骨整合情况，并研究通过粉末注射成型（PIM）技术制造的新型氧化锆植入物的表面特性，使用带有和不带有粗糙内表面的模具。
共 20 只兔子在胫骨上接受了三种具有相同几何形状的外六方植入物：机加工钛植入物、未进行模具蚀刻的 PIM 氧化锆植入物和进行模具蚀刻的 PIM 氧化锆植入物。评估了三种植入物的表面特性。进行了去除扭矩试验和组织形态计量学分析。
PIM 氧化锆植入物的粗糙度高于机加工钛植入物。PIM 氧化锆植入物的骨-植入物接触率和去除扭矩值明显高于机加工钛植入物（P<0.001）。使用粗糙模具的 PIM 氧化锆植入物的去除扭矩值明显高于未使用粗糙模具的 PIM 氧化锆植入物（P<0.001）。
PIM 氧化锆植入物的骨整合具有很大的前景，并且使用粗糙模具蚀刻技术的 PIM 可以在氧化锆植入物上产生明显粗糙的表面。
