Owusu Michael, Marfo Kwadwo Sarfo, Acheampong Godfred, Arthur Abednego, Sarpong Nimako, Im Justin, Mogeni Ondari D, Annan Augustina, Chiang Hsin-Ying, Kuo Chih-Horng, Park Se Eun, Marks Florian, Owusu-Dabo Ellis, Adu-Sarkodie Yaw
Kumasi Centre for Collaborative Research in Tropical Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Agogo Presbyterian Hospital, Agogo, Ashanti Region, Ghana.
BMC Res Notes. 2018 Apr 24;11(1):253. doi: 10.1186/s13104-018-3346-1.
Neisseria gonorrhoeae is a Gram-negative bacterium which affects the urethra, throat, rectum and cervix of patients and often associated with sexually transmitted infections. The global epidemiology of the disease is not well characterised especially in resource constraint countries due to poor diagnostic capacity and inefficient reporting systems. Although important, little is known about the propensity of this bacterium to cause sepsis in immunocompetent individuals.
A 32-year-old female presented with fever and generalised malaise to a rural hospital in Ghana. The patient had previously been diagnosed as having enteric fever from a neighbouring health facility. Blood and urine samples were collected from the patient and cultured using standard microbiological and molecular techniques. Neisseria gonorrhoeae was isolated from the blood which was resistant to penicillin, ciprofloxacin and cotrimoxazole. The patient recovered following ceftriaxone and azithromycin treatment.
This case highlights the importance of N. gonorrhoeae in causing sepsis and emphasises the need for blood culture investigation in diagnosis of patients presenting with fever.
淋病奈瑟菌是一种革兰氏阴性菌，可感染患者的尿道、咽喉、直肠和子宫颈，常与性传播感染相关。由于诊断能力差和报告系统效率低下，该病的全球流行病学特征尚不明确，尤其是在资源有限的国家。尽管很重要，但对于这种细菌在免疫功能正常个体中引起败血症的倾向知之甚少。
一名32岁女性因发热和全身不适前往加纳的一家乡村医院就诊。该患者此前在邻近的医疗机构被诊断为伤寒。采集了患者的血液和尿液样本，并使用标准微生物学和分子技术进行培养。从血液中分离出对青霉素、环丙沙星和复方新诺明耐药的淋病奈瑟菌。患者经头孢曲松和阿奇霉素治疗后康复。
本病例突出了淋病奈瑟菌在引起败血症方面的重要性，并强调了对发热患者进行血培养检查以进行诊断的必要性。
