Delahaye J P, Boissonnat P, Durand de Gévigney G
Hôpital cardiovasculaire et pneumologique Louis Pradel, Lyon.
Presse Med. 1988 May 25;17(20):1022-6.
Mechanical and medicinal therapies are widely used in coronary disease patients for emergency or semi-emergency situations. Vasodilator drugs injected into arteries that are occluded or narrowed-drugs injected into arteries that are occluded or narrowed by spasm rapidly relieve that spasm; injecting these drugs prior to angioplasty renders the myocardium more tolerant to the ischaemia created by the dilated balloon. In unstable angina coronary angioplasty has a 90 p. 100 primary success rate with immediate complications that are slightly more frequent than in stable angina; compared to historical series with medicinal treatment, angioplasty reduces the risk of myocardial infarction and/or secondary death. In evolving myocardial infarcts the respective values of intracoronary thrombolysis and angioplasty are still under discussion, although the results of recent studies tend to favour intravenous thrombolysis and secondary, elective angioplasty.
机械疗法和药物疗法在冠心病患者的紧急或半紧急情况下被广泛使用。向闭塞或狭窄的动脉注射血管扩张药物——向因痉挛而闭塞或狭窄的动脉注射药物能迅速缓解痉挛；在血管成形术前注射这些药物可使心肌对扩张球囊造成的缺血更具耐受性。在不稳定型心绞痛中，冠状动脉血管成形术的初次成功率为90%至100%，即刻并发症的发生率略高于稳定型心绞痛；与药物治疗的历史系列相比，血管成形术降低了心肌梗死和/或继发性死亡的风险。在进展性心肌梗死中，冠状动脉内溶栓和血管成形术各自的价值仍在讨论中，尽管最近的研究结果倾向于支持静脉溶栓以及二期选择性血管成形术。
