Rojas-Rojas Fernando U, López-Sánchez David, Meza-Radilla Georgina, Méndez-Canarios Ausel, Ibarra J Antonio, Estrada-de Los Santos Paulina
Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Departamento de Microbiología, Ciudad de México, México.
Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Departamento de Microbiología, Ciudad de México, México.
Rev Argent Microbiol. 2019 Jan-Mar;51(1):84-92. doi: 10.1016/j.ram.2018.01.002. Epub 2018 Apr 22.
The Burkholderia cepacia complex is a group of 22 species, which are known as opportunistic pathogens in immunocompromised people, especially those suffering from cystic fibrosis. It is also found in nosocomial infections and is difficult to eradicate due to intrinsic resistance to several antibiotics. The species have large genomes (up to 9 Mbp), distributed into 2-5 replicons. These features significantly contribute to genome plasticity, which makes them thrive in different environments like soil, water, plants or even producing nodules in legume plants. Some B. cepacia complex species are beneficial in bioremediation, biocontrol and plant-growth promotion. However, because the B. cepacia complex is involved in human infection, its use in agriculture is restricted. B. cepacia complex is being constantly studied due to the health problems that it causes and because of its agricultural potential. In this review, the history of B. cepacia complex and the most recently published information related to this complex are revised.
洋葱伯克霍尔德菌复合体是一组由22个物种组成的菌群，它们在免疫功能低下的人群中，尤其是患有囊性纤维化的患者中，被视为机会致病菌。它也存在于医院感染中，并且由于对多种抗生素具有内在抗性而难以根除。这些物种具有庞大的基因组（高达9兆碱基对），分布在2至5个复制子中。这些特征显著促进了基因组的可塑性，这使得它们能够在土壤、水、植物等不同环境中生存，甚至能在豆科植物中形成根瘤。一些洋葱伯克霍尔德菌复合体物种在生物修复、生物防治和促进植物生长方面具有益处。然而，由于洋葱伯克霍尔德菌复合体与人类感染有关，其在农业中的使用受到限制。由于它所引发的健康问题以及其农业潜力，人们一直在对洋葱伯克霍尔德菌复合体进行研究。在这篇综述中，对洋葱伯克霍尔德菌复合体的历史以及与该复合体相关的最新发表信息进行了修订。
