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[苏联卫生部N.N. 彼得罗夫肿瘤研究所培育的大鼠自发性肿瘤]

[Spontaneous tumors in rats bred at the N.N. Petrov Research Institute of Oncology of the USSR Ministry of Health].

作者信息

Anisimov V N, Iogannsen M G, Popovich I G, Romanov K P, Pliss G B

出版信息

Vopr Onkol. 1988;34(6):704-12.

PMID:2969159
Abstract

The paper discusses spontaneous tumor profile in albino rats bred at the N. N. Petrov Research Institute of Oncology of the USSR Ministry of Health (1981-1984). The overall incidence of tumors and that of malignant ones were shown to be 27.2 and 12.5%, respectively, in males and 47.4 and 16.4%, respectively, in females. Pituitary and hemopoietic tumors most frequently occurred in males (67%). Female rats most often revealed tumors of the pituitary, breast and hemopoietic system (90%). On the whole, the tumor profile proved identical in the animal population studied and that of Rappolovo farm of the USSR Academy of Medical Sciences. However, infection resistance in the former population was superior.

摘要

该论文讨论了苏联卫生部肿瘤学研究所(1981 - 1984年)培育的白化大鼠的自发性肿瘤概况。结果显示,雄性大鼠肿瘤的总体发生率和恶性肿瘤发生率分别为27.2%和12.5%,雌性大鼠分别为47.4%和16.4%。垂体和造血系统肿瘤在雄性大鼠中最常见(67%)。雌性大鼠最常出现垂体、乳腺和造血系统肿瘤(90%)。总体而言,研究的动物群体的肿瘤概况与苏联医学科学院拉波洛沃农场的动物群体相同。然而,前一群体的抗感染能力更强。

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