Csernansky J G, Kerr S, Pruthi R, Prosser E S
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305.
Brain Res. 1988 May 24;449(1-2):357-60. doi: 10.1016/0006-8993(88)91053-0.
Kindled seizures developed in rats following repeated electrical stimulation of the left CA1 region of the hippocampus. Two weeks after the final kindled seizure, the densities of dopamine (DA) D2 receptors were assayed in the left and right amygdaloid area, nucleus accumbens, and nucleus caudatus. A significant increase (107%) in the density of DA D2-receptors in the ipsilateral nucleus accumbens occurred. This finding may help to define the long-term neurochemical consequences of kindling.
对大鼠海马体左CA1区进行反复电刺激后会引发点燃式癫痫发作。在最后一次点燃式癫痫发作两周后，检测左、右杏仁核区、伏隔核和尾状核中多巴胺（DA）D2受体的密度。同侧伏隔核中DA D2受体的密度显著增加（107%）。这一发现可能有助于明确点燃式癫痫发作的长期神经化学后果。
