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同时性多器官未成熟畸胎瘤:1例报告并文献复习

Simultaneous multiple organs immature teratomas: a case report and literature review.

作者信息

Aghajanzadeh Manouchehr, Hemmati Hossein, Esmaeili Delshad Mohammad Sadegh, Rimaz Siamak, Mosaffaee Rad Omid, Jafaryparvar Zakiyeh

机构信息

Inflammatory lung diseases research Center, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Vascular Surgery and Dialysis Research Center, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Oxf Med Case Reports. 2018 Apr 19;2018(4):omy006. doi: 10.1093/omcr/omy006. eCollection 2018 Apr.

Abstract

Primary simultaneous multiple organs teratomas are extremely rare. They usually arise in the gonads, and only 1-3 % of them arise in the mediastinum. We present a case of simultaneous multiple organs immature teratomas who was admitted to Razi hospital because of cough, dyspnea, and left-side supraclavicular mass. Computed tomography (CT) showed a big mass with multiple high densities, nodular, semi-solid, heterogenic structures on the left side of the neck, left-side anterior mediastinum, right-side middle mediastinum and right-side suprarenal region. CT-guided needle biopsy was performed and histopathological study showed immature teratoma. After performing neoadjuvant therapy, the tumors were removed. The patient underwent chemo radiation therapy on the mediastinum and abdomen. On 6-months follow-up, he was asymptomatic. This case is being reported because of the rarity of multiple organs immature teratomas and informing other clinicians about managing these cases.

摘要

原发性同时性多器官畸胎瘤极为罕见。它们通常起源于性腺,其中仅有1% - 3%起源于纵隔。我们报告一例同时性多器官未成熟畸胎瘤病例,该患者因咳嗽、呼吸困难及左侧锁骨上肿块入住拉齐医院。计算机断层扫描(CT)显示,在颈部左侧、左侧前纵隔、右侧中纵隔及右侧肾上腺区域有一个巨大肿块,具有多个高密度、结节状、半实性、异质性结构。进行了CT引导下针吸活检,组织病理学研究显示为未成熟畸胎瘤。在进行新辅助治疗后,切除了肿瘤。患者接受了纵隔和腹部的放化疗。在6个月的随访中,他没有症状。报告此病例是因为多器官未成熟畸胎瘤罕见,并向其他临床医生通报此类病例的处理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0299/5909463/0658d5b842cd/omy006f01.jpg

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