子宫颈淋巴上皮瘤样癌中爱泼斯坦-巴尔病毒的证据：一例报告

Evidence of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the uterine cervix: a case report.

作者信息

Tseng L H, Tseng C J, Soong Y K, Hsueh S, Pao C C

机构信息

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

出版信息

Changgeng Yi Xue Za Zhi. 1998 Jun;21(2):184-8.

PMID:9729653

Abstract

Lymphoepithelioma-like carcinoma of the uterine cervix is very rare. A 71-year-old woman, who had cervical cancer stage IB, presented lymphoepithelioma-like carcinoma pathologically. The neoplasm revealed an undifferentiated, nonkeratinizing carcinoma, which contained prominent vesicular nucleoli histologically. Epstein-Barr virus (EBV) DNA and HPV-16 DNA were demonstrated in cancer cells when using polymerase chain reaction. The patient underwent a radical hysterectomy with bilateral pelvic lymph node dissection and bilateral salpingooophorectomy. Her postoperative course was uneventful. The literature and pathologic findings are reviewed and discussed.

摘要

子宫颈淋巴上皮瘤样癌非常罕见。一名71岁患有IB期宫颈癌的女性，病理检查显示为淋巴上皮瘤样癌。肿瘤表现为未分化的非角化性癌，组织学上可见明显的泡状核仁。使用聚合酶链反应时，在癌细胞中检测到爱泼斯坦-巴尔病毒（EBV）DNA和人乳头瘤病毒16型（HPV-16）DNA。该患者接受了根治性子宫切除术、双侧盆腔淋巴结清扫术和双侧输卵管卵巢切除术。术后恢复顺利。本文对相关文献及病理结果进行了回顾和讨论。