Clinic and Research Center of Tuberculosis, Shanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Chem Commun (Camb). 2018 May 8;54(38):4870-4873. doi: 10.1039/c8cc01542b.
Here, we propose a new fluorescence method to detect tuberculosis-related cytokine by using a target-responsive liposome activated by catalytic hairpin assembly. The method combines a DNA self-assembly based amplification process with a liposome-based signal amplification process, therefore offering a very high sensitivity.
在这里,我们提出了一种新的荧光法,通过使用催化发夹组装激活的靶标响应脂质体来检测与结核病相关的细胞因子。该方法结合了基于 DNA 自组装的扩增过程和基于脂质体的信号扩增过程,因此具有非常高的灵敏度。