Oncology Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany.
Siemens Healthcare AG, Zürich.
Invest Radiol. 2018 Aug;53(8):463-471. doi: 10.1097/RLI.0000000000000471.
The aim of this study was to evaluate the performance of an automated workflow for whole-body magnetic resonance imaging (WB-MRI), which reduces user interaction compared with the manual WB-MRI workflow.
This prospective study was approved by the local ethics committee. Twenty patients underwent WB-MRI for myopathy evaluation on a 3 T MRI scanner. Ten patients (7 women; age, 52 ± 13 years; body weight, 69.9 ± 13.3 kg; height, 173 ± 9.3 cm; body mass index, 23.2 ± 3.0) were examined with a prototypical automated WB-MRI workflow, which automatically segments the whole body, and 10 patients (6 women; age, 35.9 ± 12.4 years; body weight, 72 ± 21 kg; height, 169.2 ± 10.4 cm; body mass index, 24.9 ± 5.6) with a manual scan. Overall image quality (IQ; 5-point scale: 5, excellent; 1, poor) and coverage of the study volume were assessed by 2 readers for each sequence (coronal T2-weighted turbo inversion recovery magnitude [TIRM] and axial contrast-enhanced T1-weighted [ce-T1w] gradient dual-echo sequence). Interreader agreement was evaluated with intraclass correlation coefficients. Examination time, number of user interactions, and MR technicians' acceptance rating (1, highest; 10, lowest) was compared between both groups.
Total examination time was significantly shorter for automated WB-MRI workflow versus manual WB-MRI workflow (30.0 ± 4.2 vs 41.5 ± 3.4 minutes, P < 0.0001) with significantly shorter planning time (2.5 ± 0.8 vs 14.0 ± 7.0 minutes, P < 0.0001). Planning took 8% of the total examination time with automated versus 34% with manual WB-MRI workflow (P < 0.0001). The number of user interactions with automated WB-MRI workflow was significantly lower compared with manual WB-MRI workflow (10.2 ± 4.4 vs 48.2 ± 17.2, P < 0.0001). Planning efforts were rated significantly lower by the MR technicians for the automated WB-MRI workflow than for the manual WB-MRI workflow (2.20 ± 0.92 vs 4.80 ± 2.39, respectively; P = 0.005). Overall IQ was similar between automated and manual WB-MRI workflow (TIRM: 4.00 ± 0.94 vs 3.45 ± 1.19, P = 0.264; ce-T1w: 4.20 ± 0.88 vs 4.55 ± .55, P = 0.423). Interreader agreement for overall IQ was excellent for TIRM and ce-T1w with an intraclass correlation coefficient of 0.95 (95% confidence interval, 0.86-0.98) and 0.88 (95% confidence interval, 0.70-0.95). Incomplete coverage of the thoracic compartment in the ce-T1w sequence occurred more often in the automated WB-MRI workflow (P = 0.008) for reader 2. No other significant differences in the study volume coverage were found.
In conclusion, the automated WB-MRI scanner workflow showed a significant reduction of the examination time and the user interaction compared with the manual WB-MRI workflow. Image quality and the coverage of the study volume were comparable in both groups.
本研究旨在评估一种自动全身磁共振成像(WB-MRI)工作流程的性能,该工作流程与手动 WB-MRI 工作流程相比,减少了用户交互。
这项前瞻性研究得到了当地伦理委员会的批准。20 名患者在 3T MRI 扫描仪上接受肌病评估的 WB-MRI 检查。10 名患者(7 名女性;年龄 52 ± 13 岁;体重 69.9 ± 13.3kg;身高 173 ± 9.3cm;体重指数 23.2 ± 3.0)接受了原型自动 WB-MRI 工作流程检查,该工作流程自动对全身进行分割,而 10 名患者(6 名女性;年龄 35.9 ± 12.4 岁;体重 72 ± 21kg;身高 169.2 ± 10.4cm;体重指数 24.9 ± 5.6)接受了手动扫描。两位读者分别对每个序列(冠状 T2 加权反转恢复幅度 [TIRM] 和轴向对比增强 T1 加权 [ce-T1w] 梯度双回波序列)的整体图像质量(IQ;5 分制:5 分,优秀;1 分,差)和研究体积覆盖范围进行了评估。采用组内相关系数评估读者间的一致性。比较了两组之间的检查时间、用户交互次数和磁共振技术员的接受评分(1 分,最高;10 分,最低)。
与手动 WB-MRI 工作流程相比,自动 WB-MRI 工作流程的总检查时间明显缩短(30.0 ± 4.2 与 41.5 ± 3.4 分钟,P < 0.0001),规划时间明显缩短(2.5 ± 0.8 与 14.0 ± 7.0 分钟,P < 0.0001)。规划时间占总检查时间的 8%,而手动 WB-MRI 工作流程占 34%(P < 0.0001)。与手动 WB-MRI 工作流程相比,自动 WB-MRI 工作流程的用户交互次数明显减少(10.2 ± 4.4 与 48.2 ± 17.2,P < 0.0001)。磁共振技术员对自动 WB-MRI 工作流程的规划工作评价明显低于手动 WB-MRI 工作流程(2.20 ± 0.92 与 4.80 ± 2.39,分别为 P = 0.005)。自动和手动 WB-MRI 工作流程的整体 IQ 相似(TIRM:4.00 ± 0.94 与 3.45 ± 1.19,P = 0.264;ce-T1w:4.20 ± 0.88 与 4.55 ±.55,P = 0.423)。读者 1 和读者 2 的 TIRM 和 ce-T1w 的整体 IQ 一致性良好,组内相关系数分别为 0.95(95%置信区间:0.86-0.98)和 0.88(95%置信区间:0.70-0.95)。在 ce-T1w 序列中,自动 WB-MRI 工作流程中胸部区域的不完全覆盖更常见(P = 0.008)。在研究体积覆盖方面没有发现其他显著差异。
总之,与手动 WB-MRI 工作流程相比,自动全身磁共振成像扫描仪工作流程显著减少了检查时间和用户交互。两组的图像质量和研究体积覆盖范围相当。