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解脲支原体致膀胱结石的临床特征及腔内注射二甲基亚砜治疗: 1 例报告并文献复习

Encrusted cystitis caused by corynebacterium urealyticum: a case report with novel treatment strategy of intravesical dimethyl sulfoxide.

机构信息

Department of Urology, Kocaeli Derince Traning and Research Hospital, Kocaeli, Tukey.

Department of Urology, Kocaeli University, School of Medicine, Kocaeli, Tukey.

出版信息

Int Braz J Urol. 2018 Nov-Dec;44(6):1252-1255. doi: 10.1590/S1677-5538.IBJU.2017.0588.

DOI:10.1590/S1677-5538.IBJU.2017.0588
PMID:29697935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6442166/
Abstract

Encrusted cystitis (EC) was first described as chronic cystitis with mucosal calcification in 1914 (1). It is a very rare chronic inflammatory disease presenting with dysuria, pelvic pain and gross hematuria. Voided urine contains mucus or calcified mucopurulent stone like particles. Urinalysis always reveals alkaline pH. It may be present in healthy individuals with no predisposing etiological factors (2-4). Etiologically, previous urological diseases, immunosuppression, urinary infection with urea splitting bacteria, or urological interventions resulting in bladder mucosa trauma may also be present (5, 6). In the present case report, we describe a novel treatment for EC with intravesical dimethyl sulfoxide.

摘要

结石性膀胱炎(EC)于 1914 年首次被描述为伴有黏膜钙化的慢性膀胱炎(1)。它是一种非常罕见的慢性炎症性疾病,表现为尿痛、骨盆疼痛和肉眼血尿。排尿时尿液中含有黏液或钙化的黏液脓性结石样颗粒。尿液分析总是显示碱性 pH 值。它可能存在于没有潜在病因的健康个体中(2-4)。从病因学上讲,以前的泌尿系统疾病、免疫抑制、尿素分解细菌引起的尿路感染或导致膀胱黏膜创伤的泌尿系统干预也可能存在(5、6)。在本病例报告中,我们描述了一种新的膀胱内二甲基亚砜治疗 EC 的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a2/6442166/5a4d32e5a0f8/1677-6119-ibju-44-06-1252-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a2/6442166/65137ddad859/1677-6119-ibju-44-06-1252-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a2/6442166/5a4d32e5a0f8/1677-6119-ibju-44-06-1252-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a2/6442166/65137ddad859/1677-6119-ibju-44-06-1252-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a2/6442166/5a4d32e5a0f8/1677-6119-ibju-44-06-1252-gf02.jpg

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本文引用的文献

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Corinebacterium urealyticum: increased incidence of infection and encrusted uropathy.解脲棒杆菌:感染发生率增加及结痂性尿道病
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Encrusted Cystitis Secondary to Corynebacterium glucuronolyticum in a 57-Year-Old Man Without Predisposing Factors.一名57岁无易感因素男性继发于解脲棒状杆菌的结痂性膀胱炎
Lab Med. 2015 Spring;46(2):136-9. doi: 10.1309/LMXQP557EINXBXIF.
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Alkaline-encrusted pyelitis and cystitis: an easily missed and life-threatening urinary infection.碱性结痂性肾盂炎和膀胱炎:一种易被漏诊且危及生命的泌尿系统感染。
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Urinary glycosaminoglycans excretion and the effect of dimethyl sulfoxide in an experimental model of non-bacterial cystitis.非细菌性膀胱炎实验模型中尿糖胺聚糖排泄及二甲亚砜的作用
Int Braz J Urol. 2008 Jul-Aug;34(4):503-11; discussion 511. doi: 10.1590/s1677-55382008000400013.
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Encrusted cystitis by Corynebacterium urealyticum: a case report with novel insights into bladder lesions.解脲棒状杆菌引起的结痂性膀胱炎:一例报告及对膀胱病变的新见解
Nephrol Dial Transplant. 2008 Aug;23(8):2685-7. doi: 10.1093/ndt/gfn243. Epub 2008 May 8.
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