Ding Qian, Barker Kenneth N, Flynn Elizabeth A, Westrick Salisa C, Chang Ming, Thomas Robert E, Braxton-Lloyd Kimberly, Sesek Richard
Department of Pharmaceutical Sciences, Ferris State University, Big Rapids, MI, USA.
Department of Health Outcomes Research and Policy, Auburn University, Auburn, AL, USA.
Value Health Reg Issues. 2015 May;6:33-39. doi: 10.1016/j.vhri.2015.03.004. Epub 2015 May 16.
The purpose of this study was to explore intravenous (IV) medication errors in a Chinese hospital. The specific objectives were to 1) explore and measure the frequency of IV medication errors by direct observation and identify clues to their causes in Chinese hospital inpatient wards and 2) identify the clinical importance of the errors and find the potential risks in the preparation and administration processes of IV medications.
A prospective study was conducted by using the direct observational method to describe IV medication errors on two general surgery patient wards in a large teaching hospital in Beijing, China. A trained observer accompanied nurses during IV preparation rounds to detect medication errors. The difference in mean error rates between total parenteral nutrition (TPN) and non-TPN medications was tested by using the Mann-Whitney U test.
A final total of 589 ordered IV doses plus 4 unordered IV doses as prepared and administered to the patients was observed from August 3, 2010, to August 13, 2010. The overall error rate detected on the study ward was 12.8%. The most frequent errors by category were wrong dose (5.4%), wrong time (3.7%), omission (2.7%), unordered dose (0.7%), and extra dose (0.3%). Excluding wrong time errors, the error rate was 9.1%. Non-TPN medications had significantly higher error rates than did TPN medications including wrong time errors (P = 0.0162).
A typical inpatient in a Chinese hospital was subject to about one IV error every day. Pharmacists had a very limited role in ensuring the accuracy of IV medication preparation and administration processes.
本研究旨在探讨中国一家医院的静脉用药错误情况。具体目标为:1)通过直接观察来探究和衡量中国医院住院病房静脉用药错误的发生率,并找出其原因线索;2)确定这些错误的临床重要性,以及找出静脉用药配制和给药过程中的潜在风险。
采用直接观察法在中国北京一家大型教学医院的两个普通外科病房进行前瞻性研究,以描述静脉用药错误情况。一名经过培训的观察员在静脉用药配制过程中陪同护士,以发现用药错误。采用曼-惠特尼U检验比较全胃肠外营养(TPN)药物和非TPN药物的平均错误率差异。
2010年8月3日至2010年8月13日期间,共观察到为患者准备并使用的589剂医嘱静脉用药以及4剂非医嘱静脉用药。研究病房检测到的总体错误率为12.8%。按类别划分,最常见的错误为剂量错误(5.4%)、时间错误(3.7%)、遗漏(2.7%)、非医嘱剂量(0.7%)和额外剂量(0.3%)。排除时间错误后,错误率为9.1%。非TPN药物的错误率显著高于TPN药物,包括时间错误(P = 0.0162)。
中国医院的一名普通住院患者每天大约会遭遇一次静脉用药错误。药剂师在确保静脉用药配制和给药过程准确性方面的作用非常有限。