Schulze-Dirks A, Frosch P J
Universitäts-Hautklinik Heidelberg.
Hautarzt. 1988 Jun;39(6):375-7.
Eleven cases of contact allergy to dexpanthenol are reported (5 females, 6 males; mean age 62.4 years). Five patients suffered from a leg ulcer and/or stasis dermatitis. In five patients the sensitization occurred after the application of dexpanthenol-containing ointments to the face. Only one patient did not show sensitization to other common allergens. Three patients were sensitive to wool wax alcohols, which are present in a commonly used product. Dexpanthenol seems to be a rare sensitizer, yet clinically most relevant for patients with stasis dermatitis and multiple allergies.
报告了11例对泛醇的接触性过敏病例(5名女性,6名男性;平均年龄62.4岁)。5例患者患有腿部溃疡和/或淤积性皮炎。5例患者在面部涂抹含泛醇的药膏后发生致敏。只有1例患者对其他常见变应原未表现出致敏。3例患者对一种常用产品中含有的羊毛脂醇敏感。泛醇似乎是一种罕见的致敏原,但在临床上对淤积性皮炎和多种过敏的患者最为相关。