胰岛素受体信号传导。多种丝氨酸激酶的激活。 - Suppr

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超能文献

Insulin receptor signaling. Activation of multiple serine kinases.

作者信息

Czech M P, Klarlund J K, Yagaloff K A, Bradford A P, Lewis R E

机构信息

Department of Biochemistry, University of Massachusetts Medical Center, Worcester 01655.

出版信息

J Biol Chem. 1988 Aug 15;263(23):11017-20.

PMID:2969888

Abstract

摘要

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Insulin receptor signaling. Activation of multiple serine kinases.胰岛素受体信号传导。多种丝氨酸激酶的激活。

J Biol Chem. 1988 Aug 15;263(23):11017-20.

Serine phosphorylations triggered by the insulin receptor.由胰岛素受体引发的丝氨酸磷酸化作用。

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The role of tyrosine-and serine-threonine-protein phosphorylation in insulin action.

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Protein tyrosine kinases, protein serine kinases, and the mechanism of action of insulin.蛋白质酪氨酸激酶、蛋白质丝氨酸激酶与胰岛素的作用机制

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Insulin-activated protein kinases in fat and other cells.脂肪及其他细胞中的胰岛素激活蛋白激酶

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Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.胰岛素对正常及胰岛素抵抗小鼠骨骼肌中丝裂原活化蛋白激酶、p90核糖体S6激酶及p70 S6激酶的刺激作用。对糖原合酶调节的意义。

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The insulin receptor and tyrosine protein kinase activity.胰岛素受体与酪氨酸蛋白激酶活性。

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[The insulin receptor: an autonomous system for membrane transmission of the hormonal message].[胰岛素受体：激素信息膜传递的自主系统]

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Signaling pathways: the benefits of good communication.信号通路：良好沟通的益处。

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[Molecular basis for the development of type 2 diabetes mellitus].[2型糖尿病发生发展的分子基础]

Nihon Rinsho. 2002 Jul;60 Suppl 7:468-76.

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Front Aging Neurosci. 2017 May 3;9:118. doi: 10.3389/fnagi.2017.00118. eCollection 2017.

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Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.胰岛素通过促进新生的固醇调节元件结合蛋白-1c（SREBP-1c）的磷酸化及其与COPII囊泡的结合，增强其翻译后加工过程。

J Biol Chem. 2009 Mar 20;284(12):7518-32. doi: 10.1074/jbc.M805746200. Epub 2009 Jan 21.

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Inflammopharmacology. 1998;6(4):311-20. doi: 10.1007/s10787-998-0015-3.

Insulin signal transduction through protein kinase cascades.胰岛素通过蛋白激酶级联反应进行信号转导。

Mol Cell Biochem. 1998 May;182(1-2):31-48.

Stimulation of MAP kinase and S6 kinase by vanadium and selenium in rat adipocytes.钒和硒对大鼠脂肪细胞中丝裂原活化蛋白激酶和S6激酶的刺激作用。

Mol Cell Biochem. 1998 Jan;178(1-2):367-75. doi: 10.1023/a:1006819906820.

Angiotensin II stimulates rapid serine phosphorylation of transcription factor Stat3.

Mol Cell Biochem. 1997 May;170(1-2):171-6. doi: 10.1023/a:1006865721939.

Abnormal regulation of ribosomal protein S6 kinase by insulin in skeletal muscle of insulin-resistant humans.胰岛素抵抗人群骨骼肌中胰岛素对核糖体蛋白S6激酶的异常调节。

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The ras signaling pathway mimics insulin action on glucose transporter translocation.Ras信号通路模拟胰岛素对葡萄糖转运体易位的作用。

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Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites.鉴定胰岛素受体近膜区域中的丝氨酸-967/968为胰岛素刺激的磷酸化位点。

Biochem J. 1994 Mar 1;298 ( Pt 2)(Pt 2):471-7. doi: 10.1042/bj2980471.

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