Qiao Y J, Li X, Wu M, Yu C Q, Guo Y, Bian Z, Tan Y L, Pei P, Chen J S, Chen Z M, Lyu J, Li L M
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Apr 10;39(4):422-427. doi: 10.3760/cma.j.issn.0254-6450.2018.04.007.
To describe the regional and population-related differences in calcaneus bone mineral density (BMD) across ten regions of China. Based on the from the second Re-survey of China Kadoorie Biobank project, in which 5% of the surviving participants were interviewed during 2013-2014 and 24 677 participants aged 38-87 years were included in the study. We excluded those people with missing data for BMD and important variables. Calcaneus BMD was measured using the quantitative ultrasound bone densitometer. We analyzed four indexes, including broadband ultrasound attenuation (BUA), speed of sound (SOS), stiffness index (SI), and T score. Results The average calcaneus BMDs of the present population were: BUA (109.7±12.6) dB/MHz, SOS (1 554.7±45.6) m/s, SI (88.3±18.8), T score (-0.74±1.28). Urban residents showed higher calcaneus BMD, so as in men. The calcaneus BMD decreased by age, with a larger decline seen in women. Current smokers and postmenopausal women presented lower calcaneus BMD, while in those who frequently drank milk or yogurt or being physically more active, had higher calcaneus BMD. Calcaneus BMD varied greatly among people from the ten regions of CKB study and among participants having different demographic characteristics, lifestyle behaviors or health conditions.
描述中国十个地区跟骨骨密度（BMD）的地区差异和与人口相关的差异。基于中国嘉道理生物银行项目第二次重新调查的数据，在2013 - 2014年期间对5%的存活参与者进行了访谈，该研究纳入了24677名年龄在38 - 87岁的参与者。我们排除了那些骨密度和重要变量数据缺失的人。使用定量超声骨密度仪测量跟骨骨密度。我们分析了四个指标，包括宽带超声衰减（BUA）、声速（SOS）、硬度指数（SI）和T值。结果本研究人群的平均跟骨骨密度为：BUA（109.7±12.6）dB/MHz，SOS（1554.7±45.6）m/s，SI（88.3±18.8），T值（-0.74±1.28）。城市居民的跟骨骨密度较高，男性也是如此。跟骨骨密度随年龄下降，女性下降幅度更大。当前吸烟者和绝经后女性的跟骨骨密度较低，而经常饮用牛奶或酸奶或身体活动较多的人跟骨骨密度较高。中国慢性病前瞻性研究（CKB）的十个地区的人群以及具有不同人口统计学特征、生活方式行为或健康状况的参与者之间，跟骨骨密度差异很大。
