Takeda N, Miyake M, Kita S, Tomomitsu T, Fukunaga M
Department of Primary Health Care, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, Japan 701-01.
Calcif Tissue Int. 1996 Aug;59(2):84-8. doi: 10.1007/s002239900091.
: The speed of sound (SOS), broadband ultrasound attenuation (BUA), and the stiffness index (stiffness), which was derived from SOS and BUA, were measured on the calcaneus using the Achilles ultrasound densitometer (Lunar) in normal Japanese woman (n = 473) and men (n = 218). Sex differences and age-related changes in these variables were investigated. In addition, the bone mineral density (BMD) of the lumbar vertebrae measured by dual X-ray absorptiometry (QDR-2000, Hologic) was compared with SOS, BUA, and stiffness. There were some decreases of ultrasound variables in both young adult men and women. BMD values were similar in young adults of both sexes. BMD was relatively stable in women from 20 to 49 years, then decreased at about 1.5%/year. Ultrasound variables were higher in males than females at all ages, and they decreased from age 20 onward in both sexes with an annual loss of about 0.6%. Age-related changes in SOS, BUA, and stiffness were different from those in BMD in normal Japanese subjects. The correlations between BMD and SOS and BUA and stiffness were higher in women (r = 0.51-0.64) than in men (r = 0. 43-0.49).
使用跟腱超声骨密度仪（Lunar）对473名正常日本女性和218名正常日本男性的跟骨进行声速（SOS）、宽带超声衰减（BUA）以及由SOS和BUA得出的硬度指数（硬度）的测量。研究了这些变量的性别差异和与年龄相关的变化。此外，将通过双能X线吸收法（QDR - 2000，Hologic）测量的腰椎骨密度（BMD）与SOS、BUA和硬度进行比较。年轻成年男性和女性的超声变量均有一些下降。两性年轻成年人的BMD值相似。女性在20至49岁时BMD相对稳定，随后以每年约1.5%的速度下降。超声变量在各年龄段均为男性高于女性，并且在两性中从20岁起均下降，每年下降约0.6%。在正常日本受试者中，SOS、BUA和硬度与年龄相关的变化不同于BMD。女性中BMD与SOS、BUA和硬度之间的相关性（r = 0.51 - 0.64）高于男性（r = 0.43 - 0.49）。
