关于使用性交后试验对免疫性不育男性进行直接免疫珠试验临界值的标准化研究。
Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males.
作者信息
Koriyama Junko, Shibahara Hiroaki, Ikeda Tomoe, Hirano Yuki, Suzuki Tatsuya, Suzuki Mitsuaki
机构信息
Department of Obstetrics and Gynecology, School of Medicine, Center for Reproductive Medicine, Jichi Medical University Hospital Jichi Medical University 3311-1 Yakushiji 329-0498 Shimotsuke Tochigi Japan.
出版信息
Reprod Med Biol. 2012 Aug 9;12(1):21-25. doi: 10.1007/s12522-012-0135-8. eCollection 2013 Jan.
PURPOSE
There is a need to improve our understanding of the cut-off value of the direct immunobead test (D-IBT).
METHODS
The subjects were 26 D-IBT-positive and 140 D-IBT-negative males. The results of post coital tests (PCTs) for each subject were examined.
RESULTS
A significant difference was observed in abnormal PCTs between values <20 % and those ≥20 % ( = 0.02). However, there was no significant difference in abnormal PCTs between values <50 % and those ≥50 % ( = 0.084).
CONCLUSIONS
A cut-off value of 20 % was correlated with the possibility of conception on treatment with IUI. The D-IBT is a screening test, and the value of 20 % initially suggested by Bronson et al. seems to be more appropriate than that of 50 % in the criteria defined by the World Health Organization.
目的
有必要提高我们对直接免疫珠试验（D-IBT）临界值的理解。
方法
研究对象为26名D-IBT阳性男性和140名D-IBT阴性男性。对每个受试者的性交后试验（PCT）结果进行检查。
结果
观察到PCT异常在<20%和≥20%的值之间存在显著差异（P = 0.02）。然而，PCT异常在<50%和≥50%的值之间没有显著差异（P = 0.084）。
结论
20%的临界值与宫内人工授精（IUI）治疗受孕的可能性相关。D-IBT是一种筛查试验，布朗森等人最初提出的20%的值似乎比世界卫生组织定义标准中的50%更合适。
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