Singhakum Nissana, Laiwejpithaya Somsak, Chaopotong Pattama
Obstetrician-Gynecologist, Bangmunnak Hospital, Phichit province, Thailand. Email:
Asian Pac J Cancer Prev. 2018 Apr 27;19(4):1145-1149. doi: 10.22034/APJCP.2018.19.4.1145.
Objective: Various screening methods for cervical cancer are proved to be effective in reducing such type of cancer. We aims to introduce a new portable device as an alternative method for cervical cancer screening. The performance of device was tested on the assessment of cervical lesions using cervicograph score with the cervical cytology. Methods: 325 non-pregnant women were tested from March 2013 to August 2015. The cervical and vaginal cells from the sample were collected for cytology, then all of them received the digital cervicography conducted with our new device and scored using cervicograph score. Small pieces of cervical tissues were also collected for histologic examination. SPSS software version 18.0 was used for the statistical analysis. Results: We grouped cytology results and cervicograph scores to 2 subgroups, ≤ ASC-US and ≥ LSIL, and 0-3 points and 4-6 points, respectively. The data then correlated with histology results which sub-grouped to ≤ CIN 1 and ≥ CIN 2. The accuracy, sensitivity, specificity, and positive predictive value (PPV) of cervicograph scores 4-6 points to detect CIN 2+ were 92%, 72.41%, 97%, and 84%, respectively which were not inferior to Pap smear did. Conclusion: The digital cervicography device provides similar accuracy to Pap cytology screening and is suitable to use in the area that lacks cytoscreeners. Large scale use and generalization are required for this new device
各种宫颈癌筛查方法已被证明在降低此类癌症方面有效。我们旨在引入一种新型便携式设备作为宫颈癌筛查的替代方法。使用宫颈细胞学检查的宫颈图像评分对该设备在评估宫颈病变方面的性能进行了测试。方法：2013年3月至2015年8月对325名非孕妇进行了测试。收集样本中的宫颈和阴道细胞进行细胞学检查，然后所有人都接受了使用我们的新设备进行的数字宫颈图像检查，并使用宫颈图像评分进行评分。还收集了小块宫颈组织进行组织学检查。使用SPSS 18.0软件进行统计分析。结果：我们将细胞学结果和宫颈图像评分分别分为2个亚组，即≤非典型鳞状细胞不能明确意义（ASC-US）和≥低度鳞状上皮内病变（LSIL），以及0 - 3分和4 - 6分。然后将这些数据与组织学结果相关联，组织学结果分为≤宫颈上皮内瘤变1级（CIN 1）和≥CIN 2。宫颈图像评分4 - 6分检测CIN 2 +的准确性、敏感性、特异性和阳性预测值（PPV）分别为92%、72.41%、97%和84%，并不低于巴氏涂片检查。结论：数字宫颈图像检查设备提供了与巴氏细胞学筛查相似的准确性，适用于缺乏细胞筛查人员的地区。这种新设备需要大规模使用和推广。
