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南非老年人中的糖尿病:患病率及其对生活质量和功能残疾的影响——基于SAGE第一轮数据的评估

Diabetes in South African older adults: prevalence and impact on quality of life and functional disability - as assessed using SAGE Wave 1 data.

作者信息

Werfalli Mahmoud, Kassanjee Reshma, Kalula Sebastiana, Kowal Paul, Phaswana-Mafuya Nancy, Levitt Naomi S

机构信息

a Chronic Disease Initiative in Africa, Division of Diabetic Medicine and Endocrinology Department of Medicine , University of Cape Town , Cape Town , South Africa.

b Department of Statistical Sciences , University of Cape Town , Cape Town , South Africa.

出版信息

Glob Health Action. 2018;11(1):1449924. doi: 10.1080/16549716.2018.1449924.

Abstract

BACKGROUND

Diabetes is a chronic disease with severe late complications. It is known to impact the quality of life and cause disability, which may affect an individual's capacity to manage and maintain longer-term health and well-being.

OBJECTIVES

To examine the prevalence of self-report diabetes, and association between diabetes and each of health-related quality of life and disability amongst South Africa's older adults. To study both the direct relationship between diabetes and these two measures, as well as moderation effects, i.e. whether associations between other factors and these measures of well-being differed between individuals with diabetes and those without.

METHODS

Secondary analyses of data on participants aged 50 years and older from the Study on global AGEing and adult health (SAGE) in South Africa Wave 1 (2007-2008) were conducted. Prevalence of self-reported diabetes was assessed. Multivariable regressions describe the relationships between each of quality of life (WHOQoL) and disability (WHODAS), and diabetes, while controlling for selected socio-demographic characteristics, health risk behaviours and co-morbid conditions. In the regression models, we also investigated whether diabetes moderates the relationships between these additional factors and WHOQoL/WHODAS.

RESULTS

Self-reported diabetes prevalence was 9.2% (95% CI: 7.8,10.9) and increased with age. Having diabetes was associated with poorer WHOQoL scores (additive effect: -4.2; 95% CI: -9.2,0.9; p-value <0.001) and greater disability (multiplicative effect: 2.1; 95% CI: 1.5,2.9; p-value <0.001). Lower quality of life and greater disability were both related to not being in a relationship, lower education, less wealth, lower physical activity and a larger number of chronic conditions.

CONCLUSIONS

Diabetes is associated with lower quality of life and greater disability amongst older South Africans. Attention needs to be given to enhancing the capacity of health systems to meet the changing needs of ageing populations with diabetes in SA as well as facilitating social support networks in communities.

摘要

背景

糖尿病是一种伴有严重晚期并发症的慢性疾病。众所周知,它会影响生活质量并导致残疾,这可能会影响个人管理和维持长期健康及幸福的能力。

目的

研究南非老年人中自我报告的糖尿病患病率,以及糖尿病与健康相关生活质量和残疾之间的关联。既要研究糖尿病与这两项指标之间的直接关系,也要研究调节效应,即糖尿病患者和非糖尿病患者中其他因素与这些幸福指标之间的关联是否存在差异。

方法

对南非全球老龄化与成人健康研究(SAGE)第1波(2007 - 2008年)中50岁及以上参与者的数据进行二次分析。评估自我报告的糖尿病患病率。多变量回归描述了生活质量(世界卫生组织生活质量量表,WHOQoL)和残疾(世界卫生组织残疾评定量表,WHODAS)与糖尿病之间的关系,同时控制选定的社会人口学特征、健康风险行为和共病情况。在回归模型中,我们还研究了糖尿病是否调节这些额外因素与WHOQoL/WHODAS之间的关系。

结果

自我报告的糖尿病患病率为9.2%(95%置信区间:7.8,10.9),且随年龄增长而增加。患有糖尿病与较低的WHOQoL得分相关(相加效应:-4.2;95%置信区间:-9.2,0.9;p值<0.001)以及更大的残疾程度相关(相乘效应:2.1;95%置信区间:1.5,2.9;p值<0.001)。较低的生活质量和更大的残疾程度均与未婚、教育程度较低、财富较少、身体活动较少以及慢性病数量较多有关。

结论

在南非老年人中,糖尿病与较低的生活质量和更大的残疾程度相关。需要关注提高卫生系统满足南非糖尿病老年人群不断变化的需求的能力,以及促进社区中的社会支持网络。

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