Groarke AnnMarie, Curtis Ruth, Walsh Deirdre M J, Sullivan Francis J
School of Psychology, National University of Ireland, Galway, Ireland.
Prostate Cancer Institute, National University of Ireland Galway, Galway, Ireland.
BMC Urol. 2018 Apr 24;18(1):27. doi: 10.1186/s12894-018-0340-9.
Incidence of prostate cancer is increasing as opportunistic screening becomes widespread and life expectancy rises. Despite screening availability, research reveals conflicting results on medical outcomes, for example, disease specific mortality. However the gold standard in early diagnosis of potentially curable organ confined prostate cancer is transrectal ultrasound-guided systematic prostate biopsy (TRUS-BX). While focus has been given to medical sequalae there is a paucity of research on the psychological impact of biopsy. Awaiting biopsy may be inherently stressful but no studies to date, have assessed men's perception of stress and its impact on emotional response. This study, therefore, examines the role of stress and also personal resources namely, self-efficacy and sense of coherence in emotional adjustment in men awaiting a prostate biopsy.
Men attending a Rapid Access Prostate Cancer Clinic for a transrectal prostate biopsy (N = 114) participated in the study. They completed self report questionnaires on perceived stress (PSS), generalised self-efficacy (GSES), and sense of coherence (SOC). Adjustment was measured by the Profile of Mood States (POMS-B) which assesses tension, depression, anger, fatigue, confusion and vigour.
Hierarchical regression analyses demonstrated that the set of predictors accounted for 17%-34% of variance across six mood states and predicted 46% of total mood disturbance. Perceived stress explained variance on all domains (11%-26%) with high stress linked to poor functioning.
Perceived stress was the strongest and most consistent predictor of emotional adjustment. This is an important finding as stress appraisal has not been examined previously in this context and suggests that stress management is an important target to enhance emotional wellbeing of men attending for a prostate biopsy.
随着机会性筛查的广泛开展和预期寿命的提高，前列腺癌的发病率正在上升。尽管有筛查手段，但研究显示在医学结果方面存在相互矛盾的结果，例如疾病特异性死亡率。然而，经直肠超声引导下的系统性前列腺活检（TRUS - BX）是早期诊断潜在可治愈的局限性前列腺癌的金标准。虽然人们关注了医学后遗症，但关于活检的心理影响的研究却很少。等待活检本身可能就具有压力，但迄今为止尚无研究评估男性对压力的感知及其对情绪反应的影响。因此，本研究探讨了压力以及个人资源，即自我效能感和连贯感在等待前列腺活检的男性情绪调节中的作用。
在一家快速通道前列腺癌诊所接受经直肠前列腺活检的男性（N = 114）参与了本研究。他们完成了关于感知压力（PSS）、一般自我效能感（GSES）和连贯感（SOC）的自我报告问卷。通过情绪状态剖面图（POMS - B）来测量情绪调节，该量表评估紧张、抑郁、愤怒、疲劳、困惑和活力。
分层回归分析表明，这组预测因素解释了六种情绪状态中17% - 34%的方差，并预测了46%的总体情绪困扰。感知压力解释了所有领域的方差（11% - 26%），高压力与功能不良相关。
感知压力是情绪调节最强且最一致的预测因素。这是一项重要发现，因为此前在此背景下尚未对压力评估进行研究，这表明压力管理是提高接受前列腺活检男性情绪健康的一个重要目标。
