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利用单分子实时测序数据对嗜铁磁螺菌MSR-1全基因组序列的重新评估

Reevaluation of the Complete Genome Sequence of Magnetospirillum gryphiswaldense MSR-1 with Single-Molecule Real-Time Sequencing Data.

作者信息

Uebe René, Schüler Dirk, Jogler Christian, Wiegand Sandra

机构信息

Department of Microbiology, University of Bayreuth, Bayreuth, Germany.

Department of Microbiology, University of Bayreuth, Bayreuth, Germany

出版信息

Genome Announc. 2018 Apr 26;6(17):e00309-18. doi: 10.1128/genomeA.00309-18.

DOI:10.1128/genomeA.00309-18
PMID:29700148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5920173/
Abstract

is a key organism for understanding magnetosome formation and magnetotaxis. As earlier studies suggested a high genomic plasticity, we (re)sequenced the type strain MSR-1 and the laboratory strain R3/S1. Both sequences differ by only 11 point mutations, but organization of the magnetosome island deviates from that of previous genome sequences.

摘要

是理解磁小体形成和趋磁运动的关键生物体。正如早期研究所表明的那样,其具有高度的基因组可塑性,我们对模式菌株MSR-1和实验室菌株R3/S1进行了(重)测序。两者的序列仅相差11个点突变,但磁小体岛的组织方式与先前的基因组序列不同。

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本文引用的文献

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Magnetosome biogenesis in magnetotactic bacteria.磁小体生物发生在趋磁细菌中。
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Complete Genome Sequence of Magnetospirillum gryphiswaldense MSR-1.嗜铁钩端螺旋菌MSR-1的全基因组序列
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Inactivation of the flagellin gene flaA in Magnetospirillum gryphiswaldense results in nonmagnetotactic mutants lacking flagellar filaments.格氏嗜盐碱螺旋菌中鞭毛蛋白基因flaA的失活导致缺乏鞭毛丝的非趋磁突变体。
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