慢性炎症性脱髓鞘性多发性神经病：利用颈肌和眼肌前庭诱发肌源性电位评估前庭系统
Chronic inflammatory demyelinating polyneuropathy: evaluation of the vestibular system with cervical and ocular vestibular evoked myogenic potentials.
作者信息
Magliulo Giuseppe, Iannella Giannicola, Manno Alessandra, Libonati Laura, Onesti Emanuela, Vestri Annarita, Fegatelli Danilo Alunni, Angeletti Diletta, Pace Annalisa, Gulotta Giampiero, Gagliardi Silvia, Inghilleri Maurizio
机构信息
Department of Organi di Senso, University "Sapienza", Via Gregorio VII n.80, 00165, Rome, Italy.
Department of Neurology and Psychiatry, University "Sapienza", Rome, Italy.
出版信息
Eur Arch Otorhinolaryngol. 2018 Jun;275(6):1507-1512. doi: 10.1007/s00405-018-4981-9. Epub 2018 Apr 27.
PURPOSE
To investigate the possibility of vestibular damage in a group of patients suffering from chronic inflammatory demyelinating polyneuropathy (CIDP) using a diagnostic protocol including the caloric test, C-VEMPs and O-VEMPs.
METHODS
Twenty patients suffering from CIDP (mean age 58.5 years, range 33-80 years; 4 women and 16 men) were investigated. To assess any eventual audio-vestibular involvement, all patients of the study underwent pure tone audiometry, Fitzgerald-Hallpike caloric vestibular test, C-VEMPs and O-VEMPs.
RESULTS
In 11 patients with CIDP values of both O-VEMPs and C-VEMPs were either absent or abnormal. An absent trace at O-VEMPs testing occurred in 36% of these pathological patients, whereas an increase of n10 latency and amplitude was present in the other 64% .
CONCLUSIONS
A specific diagnostic protocol including the caloric test, C-VEMPS, O-VEMPS, could be useful when employed for identifying vestibular damage in CIDP patients.
目的
采用包括冷热试验、颈肌前庭诱发肌源性电位（C-VEMPs）和眼肌前庭诱发肌源性电位（O-VEMPs）的诊断方案，研究一组慢性炎症性脱髓鞘性多发性神经病（CIDP）患者发生前庭损害的可能性。
方法
对20例CIDP患者（平均年龄58.5岁，范围33 - 80岁；4例女性，16例男性）进行研究。为评估任何可能的听觉-前庭受累情况，研究中的所有患者均接受了纯音听力测定、Fitzgerald-Hallpike冷热前庭试验、C-VEMPs和O-VEMPs检查。
结果
11例CIDP患者的O-VEMPs和C-VEMPs值均缺失或异常。在这些病理患者中，36%的患者O-VEMPs测试时出现痕迹缺失，而另外64%的患者n10潜伏期和波幅增加。
结论
包括冷热试验、C-VEMPs、O-VEMPs的特定诊断方案，在用于识别CIDP患者的前庭损害时可能是有用的。
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